Compile Data Set for Download or QSAR
Report error Found 1218 of affinity data for UniProtKB/TrEMBL: P14598
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataKi:  2.75nMAssay Description:The affinity of ligands was determined via radioligand binding techniques using human recombinant receptors expressed in mammalian clonal cells. Deta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
WIPO WO2023288027

TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  19nMAssay Description:The affinity of ligands was determined via radioligand binding techniques using human recombinant receptors expressed in mammalian clonal cells. Deta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
WIPO WO2023288027

TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50597141(CHEMBL5197024)
Affinity DataKd:  43nMAssay Description:Binding affinity to human N-terminal TEV cleavable 6His tagged p47phox (151-285 residues) assessed as dissociation rate constant by Surface plasmon r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50597139(CHEMBL5205264)
Affinity DataKd:  214nMAssay Description:Binding affinity to human N-terminal TEV cleavable 6His tagged p47phox (151-285 residues) assessed as dissociation rate constant by Surface plasmon r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630397(CHEMBL5411448)
Affinity DataKi:  220nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKi:  240nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKi:  240nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataKi:  240nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630362(CHEMBL5427803)
Affinity DataKi:  310nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50597142(CHEMBL5177721)
Affinity DataKd:  312nMAssay Description:Binding affinity to human N-terminal TEV cleavable 6His tagged p47phox (151-285 residues) assessed as dissociation rate constant by Surface plasmon r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50094893(cid_8323 | CHEMBL88326 | 1-hydroxy-4-amino-anthraq...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM55631((E)-2-cyano-3-[(3E)-3-[[4-(diethylamino)phenyl]met...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM52827((7-amino-8-methylphenothiazin-3-ylidene)-dimethyla...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50241461(Methylene Blue anhydrous | Methylenblau | bleu de ...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM55881(MLS000768911 | cid_16682486 | 2-[3-(4-morpholinyl)...)
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630363(CHEMBL5410678)
Affinity DataKi:  420nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKi:  420nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 168 residues) probe binding to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630362(CHEMBL5427803)
Affinity DataKi:  420nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630397(CHEMBL5411448)
Affinity DataKi:  440nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKi:  440nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 168 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630398(CHEMBL5406295)
Affinity DataKi:  470nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630381(CHEMBL5412642)
Affinity DataKi:  500nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKd:  530nMAssay Description:Binding affinity to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli BL21 (DE3) pLysS assessed as dissociation constant a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50619(SMR000365576 | 1,4-diamino-9,10-dioxo-2-anthracene...)
Affinity DataIC50: 560nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630400(CHEMBL5437628)
Affinity DataKi:  560nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKi:  600nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 168 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataKi:  600nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKd:  630nMAssay Description:Binding affinity to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli BL21 (DE3) pLysS assessed as kinetics dissociation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630363(CHEMBL5410678)
Affinity DataKi:  640nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50637(MLS000738012 | cid_5354979 | SMR000393688 | 1,4-bi...)
Affinity DataIC50: 680nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630381(CHEMBL5412642)
Affinity DataKi:  680nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tag cleaved human p47phox (151 to 386 residues) expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630361(CHEMBL5413540)
Affinity DataKi:  680nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataKd:  710nMAssay Description:Binding affinity to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli BL21 (DE3) pLysS assessed as dissociation constant a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataKd:  790nMAssay Description:Binding affinity to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli BL21 (DE3) pLysS assessed as kinetics dissociation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630371(CHEMBL5410142)
Affinity DataKd:  810nMAssay Description:Binding affinity to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli BL21 (DE3) pLysS assessed as dissociation constant b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630400(CHEMBL5437628)
Affinity DataKi:  980nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630395(CHEMBL5398246)
Affinity DataKi:  1.22E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630406(CHEMBL5411421)
Affinity DataKi:  1.23E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630375(CHEMBL5439674)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM55794(cid_6701 | 1-amino-9,10-dioxoanthracene-2-carboxyl...)
Affinity DataIC50: 1.31E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630389(CHEMBL5438922)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630408(CHEMBL5439369)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM34966(N,N-dimethyl-3-(3-oxidanylidene-1,2-benzothiazol-2...)
Affinity DataIC50: 1.40E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM38875(2-spiro[3H-benzimidazole-2,1'-cyclohexane]-5-ylide...)
Affinity DataIC50: 1.42E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630348(CHEMBL5419067)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 168 residues) probe binding to His-tagged human p47phox (151 to 386 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM34340(cid_2327953 | 2-(4-methyl-3-piperidin-1-ylsulfonyl...)
Affinity DataIC50: 1.52E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50765(2-[5-(1-ethylquinolin-2-ylidene)-4-oxidanylidene-3...)
Affinity DataIC50: 1.55E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
TargetBDBP50000595(Human)
Northeastern University

WIPO
LigandPNGBDBM50630401(CHEMBL5426199)
Affinity DataKi:  1.58E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM34960(2-(2-thiazolyl)-1,2-benzothiazol-3-one | cid_23279...)
Affinity DataIC50: 1.58E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2011
Entry Details
PCBioAssay
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