TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 842nMAssay Description:Binding affinity to human GOT1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of human recombinant GOT1 using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADHMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.91E+3nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 6.82E+3nMAssay Description:Binding affinity to human GOT1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKi: 1.47E+4nMAssay Description:Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as inhibition constant by Michaelis-Menten equation base...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKd: 1.65E+4nMAssay Description:Binding affinity to GOT1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataKi: 2.02E+4nMAssay Description:Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as inhibition constant by Michaelis-Menten equ...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GOT1 (unknown origin)More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 8.46E+4nMAssay Description:Inhibition of human recombinant GOT1 expressed in Escherichia coli BL21 star DE3 cells using aspartic acid and alpha-ketoglutaric acid as substrates ...More data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetAspartate aminotransferase, cytoplasmic(Human)
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assayMore data for this Ligand-Target Pair












































