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Report error Found 12332 for UniProtKB: P29274
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451379BDBM50451379(CHEMBL43299)
Affinity DataEC50:  0.00100nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449640BDBM50449640(CHEMBL4172399)
Affinity DataIC50: 0.00160nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449648BDBM50449648(CHEMBL4161758)
Affinity DataIC50: 0.00170nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211087BDBM50211087(CHEMBL3958838)
Affinity DataIC50: 0.00190nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550812BDBM50550812(CHEMBL4756283)
Affinity DataKi:  0.00380nMAssay Description:Displacement of [3H]MSX2 from human adenosine receptor A2A expressed in HEK293 cell membranes incubated for 30 mins by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493145BDBM50493145(CHEMBL2419149)
Affinity DataKi:  0.00420nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493145BDBM50493145(CHEMBL2419149)
Affinity DataKi:  0.00420nMAssay Description:Binding affinity to human adenosine A2A receptor expressed in HEK293T cells measured by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493145BDBM50493145(CHEMBL2419149)
Affinity DataKi:  0.00420nMAssay Description:Displacement of [3H]MSX2 from human adenosine receptor A2A expressed in HEK293 cell membranes incubated for 30 mins by radioligand competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493144BDBM50493144(CHEMBL2419144)
Affinity DataKi:  0.00470nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449652BDBM50449652(CHEMBL4172264)
Affinity DataIC50: 0.00640nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315548BDBM50315548(8-(2-Thioxo-7(3-m-iodophenyl)-2-(2-furyl)thiazolo[...)
Affinity DataKi:  0.00820nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211078BDBM50211078(CHEMBL3904408)
Affinity DataIC50: 0.00830nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493151BDBM50493151(CHEMBL2419139)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449634BDBM50449634(CHEMBL4167125)
Affinity DataIC50: 0.0110nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315541BDBM50315541(8-(2-Thioxo-7(3-allyl)-2-(2-furyl)thiazole[4,3-e]1...)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493157BDBM50493157(CHEMBL2419146)
Affinity DataKi:  0.0270nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493154BDBM50493154(CHEMBL2419147)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085666BDBM50085666((2S,3S,4R,5R)-5-{6-(2,2-Diphenyl-ethylamino)-2-[2-...)
Affinity DataKi:  0.0300nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449648BDBM50449648(CHEMBL4161758)
Affinity DataIC50: 0.0360nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315545BDBM50315545(8-(2-Thioxo-7(3-m-chlorophenyl)-2-(2-furyl)thiazol...)
Affinity DataKi:  0.0380nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 761402BDBM761402(N-[4-(3-Cyanophenyl)-5-(4-methyl-6-quinolyl)thiazo...)
Affinity DataKi:  0.0400nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449640BDBM50449640(CHEMBL4172399)
Affinity DataIC50: 0.0400nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496138BDBM50496138(CHEMBL3121727)
Affinity DataKi:  0.0420nMAssay Description:Displacement of [3H]-NECA from human recombinant adenosine A2A receptor expressed in CHO cell membranes after 3 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449652BDBM50449652(CHEMBL4172264)
Affinity DataIC50: 0.0450nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496133BDBM50496133(CHEMBL3121725)
Affinity DataKi:  0.0450nMAssay Description:Displacement of [3H]-NECA from human recombinant adenosine A2A receptor expressed in CHO cell membranes after 3 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094037BDBM50094037(SCH-442416 | 2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-...)
Affinity DataKi: >0.0480nMAssay Description:Binding affinity to human adenosine A2a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094037BDBM50094037(SCH-442416 | 2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-...)
Affinity DataKi:  0.0480nMAssay Description:Inhibitory activity against human adenosine A2A receptor expressed in HEK293 cells by displacement of [3H]SCH-58261More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50094037BDBM50094037(SCH-442416 | 2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-...)
Affinity DataKi:  0.0480nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 618729BDBM618729(US20230293517, Example 4.7)
Affinity DataKi:  0.0500nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085674BDBM50085674((2S,3S,4R,5R)-5-[2-(4-Amino-cyclohexylamino)-6-(2,...)
Affinity DataKi:  0.0500nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 618748BDBM618748(US20230293517, Example 4.26)
Affinity DataKi:  0.0500nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1×LabMed (Cisbio, France...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211087BDBM50211087(CHEMBL3958838)
Affinity DataIC50: 0.0510nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50449634BDBM50449634(CHEMBL4167125)
Affinity DataIC50: 0.0590nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50457098BDBM50457098(CHEMBL4217582)
Affinity DataKi:  0.0600nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493156BDBM50493156(CHEMBL2419150)
Affinity DataKi:  0.0670nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 550787BDBM550787(7-Phenyl-8-(quinolin-6-yl)-[1,2,4]triazolo[4,3-c]p...)
Affinity DataIC50: 0.0700nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50457084BDBM50457084(CHEMBL4217248)
Affinity DataKi:  0.0700nMAssay Description:Antagonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as reduction in CGS-21680-induced cAMP level pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 761416BDBM761416(N-[4-(3-Cyanophenyl)-5-(3-methylbenzimidazol-5-yl)...)
Affinity DataKi:  0.0700nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 761364BDBM761364(4-Cyano-N-[4-(3-cyanophenyl)-5-(4-methylquinazolin...)
Affinity DataKi:  0.0700nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 550787BDBM550787(7-Phenyl-8-(quinolin-6-yl)-[1,2,4]triazolo[4,3-c]p...)
Affinity DataIC50: 0.0700nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496134BDBM50496134(CHEMBL3121726)
Affinity DataKi:  0.0720nMAssay Description:Displacement of [3H]-NECA from human recombinant adenosine A2A receptor expressed in CHO cell membranes after 3 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553403BDBM50553403(CHEMBL4747929)
Affinity DataKi:  0.0780nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 616065BDBM616065(US20230271964, Example 1-22)
Affinity DataKi:  0.0790nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 616103BDBM616103(US20230271964, Example 1-60 | US20230271964, Examp...)
Affinity DataKi:  0.0790nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 550788BDBM550788(8-(2-Chloro-6-methylpyridin-4-yl)-7-phenyl-[1,2,4]...)
Affinity DataIC50: 0.0800nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 683511BDBM683511(US20240217978, Example 166 | (2S)-2-((7-amino-2-(f...)
Affinity DataIC50: 0.0800nMAssay Description:A radioligand binding test was conducted by using [3H]-NECA (5′-N-[adenine-2,8-3H]-ethylcarboxamidoadenosine) and an adenosine A2a membrane. As...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 550788BDBM550788(8-(2-Chloro-6-methylpyridin-4-yl)-7-phenyl-[1,2,4]...)
Affinity DataIC50: 0.0800nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 550788BDBM550788(8-(2-Chloro-6-methylpyridin-4-yl)-7-phenyl-[1,2,4]...)
Affinity DataIC50: 0.0800nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 761387BDBM761387(US20250243194, Example 7.19)
Affinity DataKi:  0.0800nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
University of Virginia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085671BDBM50085671((2S,3S,4R,5R)-5-[6-(2,2-Diphenyl-ethylamino)-2-(2-...)
Affinity DataKi:  0.0800nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
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