BDBM616065 US20230271964, Example 1-22

SMILES Cc1ocnc1Cn1nc2c(-c3cc(C)nc(C)c3)c(nc(N)n2c1=O)-c1ccccc1

InChI Key InChIKey=DCRQOMNFHCQNIL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 616065   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616065(US20230271964, Example 1-22)
Affinity DataKi:  0.0790nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616065(US20230271964, Example 1-22)
Affinity DataKi:  39.8nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616065(US20230271964, Example 1-22)
Affinity DataKi:  3.96E+4nMAssay Description:Receptor binding: Evaluation of the affinity of compounds for the agonist site of the human CB-1 cannabinoid receptor in transfected CHO cells determ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent