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Report error Found 13 of affinity data for UniProtKB/TrEMBL: P49915
TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724945(US12240821, Compound 1 | US20250263383, Compound 1)
Affinity DataIC50: 6.20nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724945(US12240821, Compound 1 | US20250263383, Compound 1)
Affinity DataIC50: 6.20nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724946(US12240821, Compound 2 | US20250263383, Compound 2)
Affinity DataIC50: 23nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724946(US12240821, Compound 2 | US20250263383, Compound 2)
Affinity DataIC50: 23nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724948(US12240821, Compound 4 | US20250263383, Compound 4)
Affinity DataIC50: 98nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724948(US12240821, Compound 4 | US20250263383, Compound 4)
Affinity DataIC50: 98nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  173nMAssay Description:Binding affinity to human GMPS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724947(US12240821, Compound 3 | US20250263383, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724949(US12240821, Compound 5 | US20250263383, Compound 5)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724947(US12240821, Compound 3 | US20250263383, Compound 3)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM724949(US12240821, Compound 5 | US20250263383, Compound 5)
Affinity DataIC50: 1.00E+3nMAssay Description:The potency of the five compounds was tested against recombinant GMPS in an enzymatic assay by monitoring UV absorbance at 290 nm and by determining ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM50519499(CHEBI:8612 | Psicofuranine)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetGMP synthase [glutamine-hydrolyzing](Human)
University of Southern California

US Patent
LigandPNGBDBM50519498(Decoyinine)
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed