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Report error Found 220 of affinity data for UniProtKB/TrEMBL: P53355
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of DAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.40nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  1.40nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.40nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human GST-tagged DAPK1 catalytic domain expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged DAPK1 catalytic domain expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged DAPK1 catalytic domain expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50499279(CHEMBL3735890)
Affinity DataIC50: 12nMAssay Description:Inhibition of DAPK1 (unknown origin) by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 13nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 13.1nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 13.1nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 15.7nMAssay Description:Inhibition of human DAPK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  16nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50554817(CHEMBL4764610)
Affinity DataIC50: 23nMAssay Description:Inhibition of human DAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human GST-tagged DAPK1 catalytic domain expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50239006(CHEMBL4060481)
Affinity DataKd:  54nMAssay Description:Binding affinity to DAPK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50239006(CHEMBL4060481)
Affinity DataKd:  54nMAssay Description:Binding affinity to DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2019
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  55nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  59nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK1 (unknown origin) (1 to 289 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  69nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK1 (unknown origin) (1 to 289 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd:  72nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKd:  79nMAssay Description:HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  80nMAssay Description:Binding affinity to DAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  80nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  97nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  120nMAssay Description:Binding affinity to DAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  120nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  120nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  120nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50166251(CHEMBL3799389)
Affinity DataIC50: 140nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataIC50: 200nMAssay Description:Inhibition of DAPK1 (unknown origin) by (33P-ATP) filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataIC50: 200nMAssay Description:HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50506351(CHEMBL4439133)
Affinity DataIC50: 203nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DAPK1 catalytic domain (1 to 363 residues) expressed in baculovirus expression system by Adapta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM150751(CPR005231 (6))
Affinity DataKd:  240nMpH: 7.5Assay Description:40 µL of a solution containing 350-500 µM of CPR005231 (compound 6) were titrated into the 200 µL sample cell containing 25-55 µM DAPK1 (AA 1-285) or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50616759(CHEMBL5407750)
Affinity DataIC50: 247nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM150751(CPR005231 (6))
Affinity DataIC50: 247nMpH: 7.5 T: 2°CAssay Description:The reaction was started by adding a mix of ATP and Peptide 38 to assay plates containing DAPK1. Prior to mixing, all reagents are diluted in assay b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2015
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  270nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  270nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  270nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKd:  280nMAssay Description:HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKd:  300nMAssay Description:HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKd:  300nMAssay Description:Binding affinity to DAPK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM104066(HS43)
Affinity DataKd:  320nMAssay Description:HS38 was evaluated using a P-33 ATP filter-binding assay by the International Centre for Kinase Profiling (University of Dundee) against 124 purified...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  360nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50616760(CHEMBL5433785)
Affinity DataIC50: 370nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)
Affinity DataKd:  380nMAssay Description:Binding affinity to DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50166254(CHEMBL3797466)
Affinity DataIC50: 450nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
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