Compile Data Set for Download or QSAR
Report error Found 95 of affinity data for UniProtKB/TrEMBL: Q01177
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081499(4-Hydroxy-3-[(S)-2-oxo-3-(thieno[2,3-c]pyridine-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against plasmin in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50289436((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50289434((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074920(((R)-3-Phenyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074921([(R)-1-({(S)-Naphthalen-2-yl-[3,3,3-trifluoro-1-(4...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074915(((R)-2-Methyl-1-{(S)-2-phenyl-1-[3,3,3-trifluoro-1...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074918(((R)-2,2-Dimethyl-1-{(S)-2-phenyl-1-[3,3,3-trifluo...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50144535((R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-1-ca...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98600((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...)
Affinity DataKi:  200nM ΔG°:  -38.1kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50144551((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 251nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  270nM ΔG°:  -37.4kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50144532((2S,3R)-4-Oxo-1-[4-(6-phenyl-hexanoyl)-piperazine-...)
Affinity DataIC50: 309nMAssay Description:Inhibitory activity of compound against Plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98599((2S)-6-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...)
Affinity DataKi:  360nM ΔG°:  -36.7kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50: 380nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  400nM ΔG°:  -36.4kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 415nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50120368((2S,3R)-1-(4-tert-Butylcarbamoyl-piperazine-1-carb...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074916([(R)-2,2-Dimethyl-1-({(S)-naphthalen-2-yl-[3,3,3-t...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98601((2S)-6-[[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)...)
Affinity DataKi:  530nM ΔG°:  -35.7kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074917(Morpholine-4-carboxylic acid ((R)-2,2-dimethyl-1-{...)
Affinity DataKi:  560nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  699nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50231520(CHEMBL252937 | US8476306, 6.12 | (R)-N-[(S)-1-(4-c...)
Affinity DataKi:  750nM ΔG°:  -34.8kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98588((2S)-3-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...)
Affinity DataKi:  810nM ΔG°:  -34.7kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50031708(4-[(E)-2-(Allyl-ethoxycarbonylmethyl-carbamoyl)-pr...)
Affinity DataIC50: 873nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Val-Leu-Lys-pNA) for plasmin in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98593(methyl 4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl...)
Affinity DataKi:  960nM ΔG°:  -34.2kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  978nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.9kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98589((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...)
Affinity DataKi:  1.40E+3nM ΔG°:  -33.3kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073432(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 1.76E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50031707(4-[(E)-2-(Allyl-carboxymethyl-carbamoyl)-propenyl]...)
Affinity DataIC50: 1.83E+3nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Val-Leu-Lys-pNA) for plasmin in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50228412(methyl 1-(bis(4-acetamidophenoxy)phosphoryl)-2-(4g...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of rat plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073425(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50289435((S)-1-[(R)-2-(3,3-Dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073427(N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073426(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50289433((S)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073431(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL84575 | CHEMBL82032 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073428(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50073430(2-({(S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidi...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50031706(4-Guanidino-benzoic acid 4-dimethylcarbamoylmethox...)
Affinity DataIC50: 2.62E+3nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Val-Leu-Lys-pNA) for plasmin in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98583(4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  3.00E+3nM ΔG°:  -31.4kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98591(3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  4.20E+3nM ΔG°:  -30.6kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98584(3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  4.70E+3nM ΔG°:  -30.3kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50147046(5-Methylsulfanyl-4-[4-(5-propoxy-1-pyridin-2-yl-1H...)
Affinity DataKi:  5.00E+3nMAssay Description:In vitro binding affinity towards plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50013004(CHEMBL2371636 | 2-Acetylamino-4-methyl-pentanoic a...)
Affinity DataIC50: 5.20E+3nMAssay Description:Evaluated for the inhibition of plasmin.( no inhibition at 400 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM98592(4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...)
Affinity DataKi:  6.20E+3nM ΔG°:  -29.6kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
US Patent

TargetPlasminogen(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50144531(4-((2S,3R)-2-Carboxy-4-oxo-3-piperidin-4-ylmethyl-...)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibitory activity of compound against Plasmin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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