Compile Data Set for Download or QSAR
Report error Found 24 of affinity data for UniProtKB/TrEMBL: Q01718
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623106BDBM50623106(CHEMBL5412684)
Affinity DataKi:  0.300nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623107BDBM50623107(CHEMBL5435583)
Affinity DataKi:  0.320nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623104BDBM50623104(CHEMBL5432648)
Affinity DataKi:  0.390nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623110BDBM50623110(CHEMBL5414709)
Affinity DataKi:  0.400nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623105BDBM50623105(CHEMBL5414552)
Affinity DataKi:  0.470nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623108BDBM50623108(CHEMBL5396357)
Affinity DataKi:  0.630nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623103BDBM50623103(CHEMBL5417272)
Affinity DataKi:  0.900nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623101BDBM50623101(CHEMBL5424729)
Affinity DataKi:  0.960nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623100BDBM50623100(CHEMBL5394322)
Affinity DataKi:  1.10nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623114BDBM50623114(CHEMBL5406402)
Affinity DataKi:  1.30nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623102BDBM50623102(CHEMBL5415832)
Affinity DataKi:  1.5nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623099BDBM50623099(CHEMBL5401503)
Affinity DataKi:  1.60nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623113BDBM50623113(CHEMBL5438739)
Affinity DataKi:  1.60nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623097BDBM50623097(CHEMBL5421498)
Affinity DataKi:  2nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623115BDBM50623115(CHEMBL5414447)
Affinity DataKi:  2.10nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623111BDBM50623111(CHEMBL5403170)
Affinity DataKi:  3nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623109BDBM50623109(CHEMBL5422885)
Affinity DataKi:  3.70nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623112BDBM50623112(CHEMBL5397644)
Affinity DataKi:  4.40nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623098BDBM50623098(CHEMBL5405192)
Affinity DataKi:  4.80nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623094BDBM50623094(CHEMBL5435301)
Affinity DataKi:  21nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623095BDBM50623095(CHEMBL5396826)
Affinity DataKi:  25nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623096BDBM50623096(CHEMBL5434090)
Affinity DataKi:  36nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623093BDBM50623093(CHEMBL5438731)
Affinity DataKi:  47nMAssay Description:Displacement of [[125I]-Tyr23]-ACTH (1-39) from human MC2R incubated for 1.5 hrs by Topcount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAdrenocorticotropic hormone receptor(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169442BDBM50169442((1R,4S,6R)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 2 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed