Compile Data Set for Download or QSAR
Report error Found 418 of affinity data for UniProtKB/TrEMBL: Q03732
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50248008(CHEBI:473990 | BMS-200475-01 | Baraclude | Entecav...)
Affinity DataEC50:  0.240nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  1nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50592300(CHEMBL5187151)
Affinity DataEC50:  1.60nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530984(CHEMBL4077913)
Affinity DataEC50:  2nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530997(CHEMBL4587268)
Affinity DataEC50:  2nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530997(CHEMBL4587268)
Affinity DataEC50:  2nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530984(CHEMBL4077913)
Affinity DataEC50:  2nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586546(CHEMBL5091507)
Affinity DataEC50:  2.70nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247811(CHEMBL4078766)
Affinity DataEC50:  3nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50531001(CHEMBL4446995)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50585292(CHEMBL5072925)
Affinity DataEC50:  3nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication by particle gel assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530983(CHEMBL4577679)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50237769(CHEMBL4064672)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50237769(CHEMBL4064672)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530983(CHEMBL4577679)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM580439(US11491148, Compound C33R* | US11491148, Compound ...)
Affinity DataEC50:  3nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50531001(CHEMBL4446995)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586547(CHEMBL5082468)
Affinity DataEC50:  3.40nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50592294(CHEMBL5188597)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50585291(CHEMBL5075092)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication by particle gel assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50592295(CHEMBL5190770)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586555(CHEMBL5077493)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586559(CHEMBL5093261)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586545(CHEMBL5091824)
Affinity DataEC50:  4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50531002(CHEMBL4517178)
Affinity DataEC50:  5nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586552(CHEMBL5094954)
Affinity DataEC50:  5nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50592299(CHEMBL5208675)
Affinity DataEC50:  5nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50585294(CHEMBL5085778)
Affinity DataEC50:  5nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication by particle gel assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247657(CHEMBL4076401)
Affinity DataEC50:  5nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50531002(CHEMBL4517178)
Affinity DataEC50:  5nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530995(CHEMBL4580643)
Affinity DataEC50:  5nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530995(CHEMBL4580643)
Affinity DataEC50:  5nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586549(CHEMBL5084337)
Affinity DataEC50:  5.30nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586551(CHEMBL5081800)
Affinity DataEC50:  5.30nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50450818(CHEMBL4211812)
Affinity DataEC50:  6nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586553(CHEMBL5091055)
Affinity DataEC50:  6nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM580406(US11491148, Compound C16)
Affinity DataEC50:  6nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM580427(US11491148, Compound C31R* | US11491148, Compound ...)
Affinity DataEC50:  7nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586548(CHEMBL5085383)
Affinity DataEC50:  7.30nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50585289(CHEMBL5089762)
Affinity DataEC50:  9nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication by particle gel assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586554(CHEMBL5091198)
Affinity DataEC50:  9nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50592297(CHEMBL5187902)
Affinity DataEC50:  9nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50586554(CHEMBL5091198)
Affinity DataEC50:  9nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50450790(CHEMBL4210470)
Affinity DataEC50:  10nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530991(CHEMBL4447713)
Affinity DataEC50:  10nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530992(CHEMBL4449828)
Affinity DataEC50:  10nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM580447(US11491148, Compound C36)
Affinity DataEC50: <10nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50530991(CHEMBL4447713)
Affinity DataEC50:  10nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM580407(US11491148, Compound C17)
Affinity DataEC50:  10nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50585283(CHEMBL5075793)
Affinity DataEC50:  10nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication by particle gel assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
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