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Found 25 Enz. Inhib. hit(s) with Target = 'Capsid protein' and Ligand = 'BDBM50247812'
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  12nMAssay Description:Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  700nMAssay Description:Inhibition of capsid in HBV infected in human HepAD38 cells assessed as reduction in tetracycline-induced cccDNA formation by measuring reduction in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  46nMAssay Description:Inhibition of reverse transcriptase M204I/S202G/M250V triple mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  18nMAssay Description:Inhibition of reverse transcriptase M204I/S202G/M250V triple mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  87nMAssay Description:Inhibition of reverse transcriptase M204I/S202G double mutant expressing entecavir-resistant hepatitis B virus capsid assembly in human Huh7 cells as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  14nMAssay Description:Inhibition of wild type hepatitis B virus capsid assembly in human HepG2.215 cells assessed as reduction in intracellular DNA levels measured on day ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  17nMAssay Description:Inhibition of wild type hepatitis B virus capsid assembly in human HepG2.215 cells assessed as reduction in intracellular DNA levels measured on day ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  38nMAssay Description:Inhibition of wild type hepatitis B virus capsid assembly in human HepG2.215 cells assessed as reduction in intracellular DNA levels measured on day ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  31nMAssay Description:Inhibition of wild type hepatitis B virus capsid assembly in human HepG2.215 cells assessed as reduction in intracellular DNA levels measured on day ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  34nMAssay Description:Inhibition of wild type hepatitis B virus capsid assembly in human HepG2.215 cells assessed as reduction in intracellular DNA levels measured on day ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  19nMAssay Description:Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  10nMAssay Description:Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  33nMAssay Description:Inhibition of reverse transcriptase L180M/M204V double mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  92nMAssay Description:Inhibition of reverse transcriptase M204I mutant expressing telbivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  15nMAssay Description:Inhibition of reverse transcriptase M204I/V173L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  11nMAssay Description:Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  19nMAssay Description:Inhibition of reverse transcriptase M204I/VI73L double mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  34nMAssay Description:Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  34nMAssay Description:Inhibition of entecavir-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  39nMAssay Description:Inhibition of entecavir-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  20nMAssay Description:Inhibition of telbivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  12nMAssay Description:Inhibition of telbivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in intracellular DNA levels...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  20nMAssay Description:Inhibition of lamivudine-resistant wild type hepatitis B virus capsid assembly in human Huh7 cells assessed as reduction in secreted DNA levels measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  92nMAssay Description:Inhibition of reverse transcriptase M204I mutant expressing lamivudine-resistant hepatitis B virus capsid assembly in human Huh7 cells assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Sunshine Lake Pharma

Curated by ChEMBL
LigandPNGBDBM50247812(CHEMBL3742114)
Affinity DataEC50:  1nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed