TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 0.00500nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 0.150nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to LPA2 receptor (unknown origin) by free solution assay-compensated interferometric reader (FSA-CIR) techniqueMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at LPA2 receptor (unknown origin) expressed in MEF cells assessed as increase in intracellular calcium level measured every 3.42 sec...More data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 6.80nMAssay Description:Agonistic activity against lysophosphatidic acid receptor 2 using [35S]GTP-gamma-S as radioligand tested in vitroMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of LPA2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of LPA2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of LPA2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of LPA2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of LPA2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 20.8nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 21.1nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 21.8nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 28.3nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonistic activity against lysophosphatidic acid receptor 2 using [35S]GTP-gamma-S as radioligand tested in vitroMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 108nMAssay Description:Agonistic activity against lysophosphatidic acid receptor 2 using [35S]GTP-gamma-S as radioligand tested in vitroMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human LPA2 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 112nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 116nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataEC50: 117nMAssay Description:Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assayMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
TargetLysophosphatidic acid receptor 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair










































