BDBM50148435 CHEMBL119116::[3-(3,5-Dichloro-4-octyloxy-benzylamino)-propyl]-phosphonic acid

SMILES CCCCCCCCOc1c(Cl)cc(CNCCCP(O)(O)=O)cc1Cl

InChI Key InChIKey=VEAJEWXYGKUGPH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148435   

TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148435(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 5 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148435(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148435(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 5 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148435(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 3 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148435(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)
Affinity DataIC50:  6.60nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed