Compile Data Set for Download or QSAR
Report error Found 9892 of affinity data for UniProtKB/TrEMBL: Q9NYK1
TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719098(US20250049780, Example 25)
Affinity DataEC50:  0.0500nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM655471(US11912703, Example 454)
Affinity DataIC50: 0.0500nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50615023(CHEMBL5266091 | US20250049780, Example 26)
Affinity DataEC50:  0.0700nMAssay Description:Antagonist activity at human TLR7 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719129(US20250049780, Example 55)
Affinity DataEC50:  0.0700nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427894(US10544143, Example 328 | US10544143, Example 329 ...)
Affinity DataIC50: 0.0800nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM516908(US11053244, Example 328 | US11053244, Example 329)
Affinity DataIC50: 0.0800nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427894(US10544143, Example 328 | US10544143, Example 329 ...)
Affinity DataIC50: 0.0800nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428633(US10544143, Example 1069 | US10544143, Example 107...)
Affinity DataIC50: 0.0900nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428633(US10544143, Example 1069 | US10544143, Example 107...)
Affinity DataIC50: 0.0900nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428633(US10544143, Example 1069 | US10544143, Example 107...)
Affinity DataIC50: 0.0900nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719102(US20250049780, Example 29)
Affinity DataEC50:  0.100nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50586260(CHEMBL5079910)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human TLR7 expressed in human PBMC cells assessed as inhibition of ssRNA stimulated IFNalpha level preincubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM273647(US10071079, Example 432 | US10478424, Example 432)
Affinity DataIC50: 0.100nMT: 2°CAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM273647(US10071079, Example 432 | US10478424, Example 432)
Affinity DataIC50: 0.100nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50615020(CHEMBL5267703)
Affinity DataEC50:  0.110nMAssay Description:Antagonist activity at human TLR7 expressed in human PBMC cells preincubated for 1 hr followed by GS-986 stimulation measured after 6 hrs by electroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50615023(CHEMBL5266091 | US20250049780, Example 26)
Affinity DataEC50:  0.110nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719074(US20250049780, Example 1)
Affinity DataEC50:  0.110nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427907(US10544143, Example 341 | US10544143, Example 342 ...)
Affinity DataIC50: 0.120nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427907(US10544143, Example 341 | US10544143, Example 342 ...)
Affinity DataIC50: 0.120nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427907(US10544143, Example 341 | US10544143, Example 342 ...)
Affinity DataIC50: 0.120nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427891(US10544143, Example 325 | US10544143, Example 326 ...)
Affinity DataIC50: 0.130nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427891(US10544143, Example 325 | US10544143, Example 326 ...)
Affinity DataIC50: 0.130nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427891(US10544143, Example 325 | US10544143, Example 326 ...)
Affinity DataIC50: 0.130nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427896(US10544143, Example 330 | US10544143, Example 331 ...)
Affinity DataIC50: 0.140nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427896(US10544143, Example 330 | US10544143, Example 331 ...)
Affinity DataIC50: 0.140nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427896(US10544143, Example 330 | US10544143, Example 331 ...)
Affinity DataIC50: 0.140nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719092(US20250049780, Example 19)
Affinity DataEC50:  0.140nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719101(US20250049780, Example 28)
Affinity DataEC50:  0.150nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM655198(US11912703, Example 81)
Affinity DataIC50: 0.150nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM655196(US11912703, Example 107 | US11912703, Example 80)
Affinity DataIC50: 0.160nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427741(US10544143, Example 174 | US10730877, Example 199 ...)
Affinity DataIC50: 0.160nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427741(US10544143, Example 174 | US10730877, Example 199 ...)
Affinity DataIC50: 0.160nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427762(US10544143, Example 195 | US10544143, Example 199)
Affinity DataIC50: 0.160nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428604(US10544143, Example 1052 | US10544143, Example 104...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427884(US10544143, Example 318 | US10544143, Example 323 ...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428604(US10544143, Example 1052 | US10544143, Example 104...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427884(US10544143, Example 318 | US10544143, Example 323 ...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427884(US10544143, Example 318 | US10544143, Example 323 ...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428604(US10544143, Example 1052 | US10544143, Example 104...)
Affinity DataIC50: 0.170nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428090(US10544143, Example 525 | US10730877, Example 525 ...)
Affinity DataIC50: 0.180nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428090(US10544143, Example 525 | US10730877, Example 525 ...)
Affinity DataIC50: 0.180nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428090(US10544143, Example 525 | US10730877, Example 525 ...)
Affinity DataIC50: 0.180nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM655200(US11912703, Example 110 | US11912703, Example 82)
Affinity DataIC50: 0.180nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427909(US10544143, Example 343 | US10544143, Example 344 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428372(US10544143, Example 808 | US10544143, Example 838 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427909(US10544143, Example 343 | US10544143, Example 344 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428372(US10544143, Example 808 | US10544143, Example 838 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM427909(US10544143, Example 343 | US10544143, Example 344 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM428372(US10544143, Example 808 | US10544143, Example 838 ...)
Affinity DataIC50: 0.190nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM273910(US10071079, Example 696 | US10478424, Example 696)
Affinity DataIC50: 0.200nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2020
Entry Details
US Patent

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