aid
Article Title
Organization
Deposition
Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in HeLa Cells
Southern Research Institute
11/09/16
Counterscreen for activators of Transthyretin (TTR) transcription: Luminescence-based cell-based high throughput dose response assay to identify inhibitors of Transthyretin (TTR) transcription in HuH7 hepatoma cells
The Scripps Research Institute Molecular Screening Center
01/12/15
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1).
The Scripps Research Institute Molecular Screening Center
01/12/15
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
The Scripps Research Institute Molecular Screening Center
01/12/15
Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization
The Scripps Research Institute Molecular Screening Center
08/09/14
TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration
The Scripps Research Institute Molecular Screening Center
08/09/14
Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response assay to identify agonists of the Liver-X-Receptor (LXR).
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR)
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based screening assay to identify agonists of the Liver-X-Receptor (LXR).
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput dose response assay to identify inhibitors of ADAM17
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for exosite inhibitors of ADAM17: Fluorescence resonance energy transfer (FRET)-based biochemical high throughput dose response assay to identify inhibitors of ADAM10
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for inhibitors of COUP-TFII (NR2F2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)
The Scripps Research Institute Molecular Screening Center
08/08/14
Counterscreen for inhibitors of phospholipase C isozymes (PLC-B3): Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1)
The Scripps Research Institute Molecular Screening Center
08/08/14
Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay
Burnham Center For Chemical Genomics
08/08/14
Epi Absorbance-based biochemical high throughput dose response assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2)
The Scripps Research Institute Molecular Screening Center
08/08/14
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]
The Scripps Research Institute Molecular Screening Center
08/08/14
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]
The Scripps Research Institute Molecular Screening Center
08/08/14
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of phospholipase C isozymes (PLC-B3)
The Scripps Research Institute Molecular Screening Center
08/08/14
Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1)
The Scripps Research Institute Molecular Screening Center
08/08/14
Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
The Scripps Research Institute Molecular Screening Center
08/08/14
Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12)
The Scripps Research Institute Molecular Screening Center
08/08/14
Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12)
The Scripps Research Institute Molecular Screening Center
08/08/14
QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM10.
The Scripps Research Institute Molecular Screening Center
08/08/14
QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM17
The Scripps Research Institute Molecular Screening Center
08/08/14
QFRET-based biochemical high throughput dose response assay to identify inhibitors of human group III secreted phospholipase A2 enzyme (HGIII-sPLA2)
The Scripps Research Institute Molecular Screening Center
08/08/14
TRFRET-based biochemical high throughput dose response assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide
The Scripps Research Institute Molecular Screening Center
08/08/14
TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC)
The Scripps Research Institute Molecular Screening Center
08/08/14
Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen
The Scripps Research Institute Molecular Screening Center
09/18/13
Late stage assay provider counterscreen for TLR9 inhibitors: Luminescence-based assay to identify inhibitors of TLR9-dependent cell activation using RAW264.7 cells
The Scripps Research Institute Molecular Screening Center
09/18/13
Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2)
The Scripps Research Institute Molecular Screening Center
09/18/13
Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
The Scripps Research Institute Molecular Screening Center
06/21/13
Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)
The Scripps Research Institute Molecular Screening Center
06/21/13
Confirmatory FRET assay using full length substrates for Botulinum neurotoxin light chain A protease, with Powder Set01
Nmmlsc
06/21/13
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response.
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose reponse assay to identify nonselective Ga16 agonists
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify TAAR1 Agonists
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for inhibitors of T-cell receptor (TCR)-CD3 interaction: Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled BSA probe
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay
The Scripps Research Institute Molecular Screening Center
06/21/13
Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)
The Scripps Research Institute Molecular Screening Center
06/21/13
Dose Response confirmation of uHTS hits for a small molecule Caspase-8 TRAIL sensitizers in a luminescence panel assay
Burnham Center For Chemical Genomics
06/21/13
Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in a fluorescence-based, Lymphoid Phosphatase (PTPN22, LYP-1) selectivity Assay
Burnham Center For Chemical Genomics
06/21/13
Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay
Burnham Center For Chemical Genomics
06/21/13
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis
The Scripps Research Institute Molecular Screening Center
06/21/13
Fluorescence-based biochemical high throughput dose response assay to identify molecules that bind r(CAG) RNA repeats
The Scripps Research Institute Molecular Screening Center
06/21/13
Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe
The Scripps Research Institute Molecular Screening Center
06/21/13
Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1)
The Scripps Research Institute Molecular Screening Center
06/21/13
Fluorescence-based cell-based high throughput dose response assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1)
The Scripps Research Institute Molecular Screening Center
06/21/13
Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3).
The Scripps Research Institute Molecular Screening Center
06/21/13
Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS)
The Scripps Research Institute Molecular Screening Center
06/21/13
Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1
The Scripps Research Institute Molecular Screening Center
06/21/13
Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)
The Scripps Research Institute Molecular Screening Center
06/21/13
Luminescence-based cell-based high throughput dose response assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)
The Scripps Research Institute Molecular Screening Center
06/21/13
Vibrio cholerae assay for pro-quorum sensing small molecules
Southern Research Specialized Biocontainment Screening Center
06/21/13
Counter screen for HTS for Beta-2AR agonists with FAP-tagged human CCR5 with Powderset2
Nmmlsc
06/20/13
Counterscreen for discovery of small molecules that bind to the HIV-1-gp120 binding antibody, PG9
The Scripps Research Institute Molecular Screening Center
06/20/13
Counterscreen for discovery of small molecules that bind to the HIV-1-gp120 binding antibody, PG9
The Scripps Research Institute Molecular Screening Center
06/20/13
Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2)
The Scripps Research Institute Molecular Screening Center
06/20/13
Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5)
The Scripps Research Institute Molecular Screening Center
06/20/13
Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of Hepatocyte nuclear factor 4 (HNF4) dimerization
The Scripps Research Institute Molecular Screening Center
06/20/13
Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay
Burnham Center For Chemical Genomics
06/20/13
Dose Response confirmation of small molecule modulators of the interaction between CendR and NRP-1 in a panel assay
Burnham Center For Chemical Genomics
06/20/13
Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format
Burnham Center For Chemical Genomics
06/20/13
Dose Response counterscreen of small molecule antagonists of the CXCR6 receptor using a CXCR5 receptor luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
06/20/13
Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a kinetic FRET assay
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of uHTS identification of HIF-2a Inhibitors in a luminesence assay
Burnham Center For Chemical Genomics
06/20/13
Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2
Burnham Center For Chemical Genomics
06/20/13
Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay
Burnham Center For Chemical Genomics
06/20/13
Dose responses of compounds that inhibit the Choline Transporter (CHT) in a 3H-choline uptake radioactive assay
Johns Hopkins Ion Channel Center
06/20/13
Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 in a Caspase-3 Fluorescence assay
Burnham Center For Chemical Genomics
06/20/13
Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate
Burnham Center For Chemical Genomics
06/20/13
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)
The Scripps Research Institute Molecular Screening Center
06/20/13
Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1)
The Scripps Research Institute Molecular Screening Center
06/20/13
Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2)
The Scripps Research Institute Molecular Screening Center
06/20/13
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5)
The Scripps Research Institute Molecular Screening Center
06/20/13
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) produced in HEK293T cells
The Scripps Research Institute Molecular Screening Center
06/20/13
SAR analysis of small molecule activators of alpha dystroglycan glycosylation
Burnham Center For Chemical Genomics
06/20/13
TRFRET-based biochemical high throughput dose response assay for small molecules that bind to the HIV-1-gp120 binding antibody, PG9
The Scripps Research Institute Molecular Screening Center
06/20/13
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the Lymphoid Phosphatase (PTPN22) Inhibition Assay
Burnham Center For Chemical Genomics
06/25/12
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
Burnham Center For Chemical Genomics
06/25/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, compounds from Powder Set 01
Nmmlsc
06/25/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Powder Set 01
Nmmlsc
06/25/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Lethal Factor protease, compounds from Powder Set 01
Nmmlsc
06/25/12
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
The Scripps Research Institute Molecular Screening Center
06/19/12
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors
The Scripps Research Institute Molecular Screening Center
06/19/12
Counterscreen for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
The Scripps Research Institute Molecular Screening Center
06/19/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr1 with Cherry Pick2 compound set
Nmmlsc
06/19/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Cherry Pick2 compound set
Nmmlsc
06/19/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Cherry Pick2 compound set
Nmmlsc
06/19/12
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
Burnham Center For Chemical Genomics
06/19/12
Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01
Nmmlsc
06/19/12
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Powder Set1
Nmmlsc
06/19/12
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
Burnham Center For Chemical Genomics
06/19/12
Dose Response selectivity of inhibitors of Striatal-Enriched Phosphatase (STEP) in a SHP2 (PTPN11) Inhibition Assay
Burnham Center For Chemical Genomics
06/19/12
Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay
Burnham Center For Chemical Genomics
06/19/12
Dose Response with BCECF Assay for V-ATPase inhibitors that increase vacuolar pH, Powder Set 1
Nmmlsc
06/19/12
Dose response confirmation of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay
Burnham Center For Chemical Genomics
06/19/12
Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay
Burnham Center For Chemical Genomics
06/19/12
Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay
Burnham Center For Chemical Genomics
06/19/12
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
Burnham Center For Chemical Genomics
06/19/12
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2
Nmmlsc
06/19/12
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3
Nmmlsc
06/19/12
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
Johns Hopkins Ion Channel Center
06/19/12
Dose-response confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay
Burnham Center For Chemical Genomics
06/19/12
Dose-response secondary confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay using Cy5 labeled peptide
Burnham Center For Chemical Genomics
06/19/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, compounds from Cherry Pick 02
Nmmlsc
06/19/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Cherry Pick 02
Nmmlsc
06/19/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Lethal Factor protease, compounds from Cherry Pick 02
Nmmlsc
06/19/12
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
The Scripps Research Institute Molecular Screening Center
06/19/12
Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1)
The Scripps Research Institute Molecular Screening Center
06/19/12
SAR analysis of small molecule Activators of Apaf-1 in a Fluorescent assay - set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule Inhibitors of Apaf-1 in a Fluorescent assay - set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule activators of Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay - Set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay - Set 2
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of tim23-1 yeast via a luminescent assay
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
Burnham Center For Chemical Genomics
06/19/12
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
Burnham Center For Chemical Genomics
06/19/12
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
The Scripps Research Institute Molecular Screening Center
06/19/12
Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)
The Scripps Research Institute Molecular Screening Center
06/18/12
Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1)
The Scripps Research Institute Molecular Screening Center
06/18/12
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2
Nmmlsc
06/18/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, compounds from Cherry Pick 01
Nmmlsc
06/18/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Cherry Pick 01
Nmmlsc
06/18/12
High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Lethal Factor protease, compounds from Cherry Pick 01
Nmmlsc
06/18/12
Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
The Scripps Research Institute Molecular Screening Center
06/18/12
PLD1 purified enzyme concentration response
Vanderbilt Specialized Chemistry Center
06/18/12
PLD2 purified enzyme concentration response
Vanderbilt Specialized Chemistry Center
06/18/12
SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay
Burnham Center For Chemical Genomics
06/18/12
TRFRET-based biochemical high throughput dose response assay for inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)
The Scripps Research Institute Molecular Screening Center
06/18/12
Dose Response Assay for Inhibitors of the beta-Arrestin-Adaptor Protein 2 Interaction for Cherry Pick 1
Nmmlsc
01/06/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr1 with Hit compounds from Cherry Pick1
Nmmlsc
01/06/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Hit compounds from Cherry Pick1
Nmmlsc
01/06/12
Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Hit compounds from Cherry Pick1
Nmmlsc
01/06/12
Dose Response confirmation of uHTS Activators of the Apaf-1 Pathway in Fluorescent format
Burnham Center For Chemical Genomics
01/06/12
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 1
Nmmlsc
01/06/12
Dose Response validation of Activators of Apaf-1 using a Fluorescent Interference Counterscreen assay
Burnham Center For Chemical Genomics
01/06/12
Dose response assay for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay II
Johns Hopkins Ion Channel Center
01/06/12
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B Set 2
Burnham Center For Chemical Genomics
01/06/12
Dose response confirmation of uHTS hits for Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay
Burnham Center For Chemical Genomics
01/06/12
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2
Burnham Center For Chemical Genomics
01/06/12
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset1
Nmmlsc
01/06/12
Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based dose response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) assay for HTS compounds
The Scripps Research Institute Molecular Screening Center
01/06/12
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
Burnham Center For Chemical Genomics
01/06/12
SAR analysis of small molecule activators of the MazEF TA System via a fluorescence-based single-stranded RNase assay
Burnham Center For Chemical Genomics
01/06/12
Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization
The Scripps Research Institute Molecular Screening Center
01/05/12
Dose Response validation of Inhibitors of Apaf-1 using a Fluorescent Interference Counterscreen assay
Burnham Center For Chemical Genomics
01/05/12
Dose response confirmation of uHTS hits for Apaf-1 in a Fluorescent assay
Burnham Center For Chemical Genomics
01/05/12
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
Burnham Center For Chemical Genomics
01/05/12
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
Burnham Center For Chemical Genomics
01/05/12
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
Burnham Center For Chemical Genomics
01/05/12
Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter
The Scripps Research Institute Molecular Screening Center
01/05/12
SAR analysis counterscreen of small molecule antagonists of the CCR6 receptor using an APJ receptor luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
01/05/12
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
The Scripps Research Institute Molecular Screening Center
01/04/12
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
Burnham Center For Chemical Genomics
01/04/12
Dose Response orthogonal assay utilizing the direct end-point detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase
Burnham Center For Chemical Genomics
01/04/12
Dose Response orthogonal kinetic assay utilizing the direct detection of NADPH for uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase
Burnham Center For Chemical Genomics
01/04/12
Fluorescence-based cell-based high throughput dose response assay for inhibitors of TLR9-MyD88 binding
The Scripps Research Institute Molecular Screening Center
01/04/12
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
Burnham Center For Chemical Genomics
01/04/12
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
01/04/12
Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex
The Scripps Research Institute Molecular Screening Center
08/04/11
Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex
The Scripps Research Institute Molecular Screening Center
08/04/11
Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay
Burnham Center For Chemical Genomics
08/04/11
Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay
Burnham Center For Chemical Genomics
08/04/11
Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay
Burnham Center For Chemical Genomics
08/04/11
Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R1A (PKA-R1A) complex
The Scripps Research Institute Molecular Screening Center
08/04/11
Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex
The Scripps Research Institute Molecular Screening Center
08/04/11
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
Burnham Center For Chemical Genomics
08/04/11
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction in luminescent format
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of activators of hexokinase domain containing I (HKDC1)
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1)
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen.
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
Burnham Center For Chemical Genomics
08/03/11
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
Burnham Center For Chemical Genomics
08/03/11
Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
Nmmlsc
08/03/11
Dose Response of inhibitors of GRK2 binding with RNA aptamer, Cherry Pick 1
Nmmlsc
08/03/11
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
The Scripps Research Institute Molecular Screening Center
08/03/11
Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B.
Burnham Center For Chemical Genomics
08/03/11
Dose response counterscreen for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-3
The Scripps Research Institute Molecular Screening Center
08/03/11
Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
The Scripps Research Institute Molecular Screening Center
08/03/11
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
The Scripps Research Institute Molecular Screening Center
08/03/11
Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
The Scripps Research Institute Molecular Screening Center
08/03/11
Fluorescence-polarization-based biochemical polarscreen dose response binding assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg)
The Scripps Research Institute Molecular Screening Center
08/03/11
HTS Dose response counterscreen for assays utilizing the enzyme, beta-galactosidase - Set 3
Burnham Center For Chemical Genomics
08/03/11
Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
The Scripps Research Institute Molecular Screening Center
08/03/11
Late stage assay provider counterscreen for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg): Luminescence-based cell-based dose response assay for partial agonists of the peroxisome proliferator-activated receptor alpha (PPARA).
The Scripps Research Institute Molecular Screening Center
08/03/11
Late-stage fluorescence dose response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): purchased compounds EC50
The Scripps Research Institute Molecular Screening Center
08/03/11
Late-stage radioligand binding dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): PDSP screen Ki Set 2
The Scripps Research Institute Molecular Screening Center
08/03/11
Luminescence-based cell-based assay provider high throughput dose response assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg)
The Scripps Research Institute Molecular Screening Center
08/03/11
SAR Analysis for the identification of selective inhibits of the transient receptor potential cation channel C4 (TRPC4): Automated Electrophysiology_2
Johns Hopkins Ion Channel Center
08/03/11
TR-FRET-based biochemical dose response competitive binding lanthascreen assay for partial agonists of the peroxisome proliferator-activated receptor gamma (PPARg)
The Scripps Research Institute Molecular Screening Center
08/03/11
Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3
The Scripps Research Institute Molecular Screening Center
08/02/11
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
The Scripps Research Institute Molecular Screening Center
08/02/11
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
The Scripps Research Institute Molecular Screening Center
08/02/11
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
Burnham Center For Chemical Genomics
08/02/11
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
Burnham Center For Chemical Genomics
08/02/11
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
Burnham Center For Chemical Genomics
08/02/11
Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4)
The Scripps Research Institute Molecular Screening Center
08/02/11
Inhibitors of T-Type Calcium Channels
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
08/02/11
Inhibitors of T-Type Calcium Channels (SynthLib1)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
08/02/11
Inhibitors of T-Type Calcium Channels (SynthLib2)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
08/02/11
Intein inhibitors as potential Tuberculosis drugs
Southern Research Specialized Biocontainment Screening Center
08/02/11
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set)
The Scripps Research Institute Molecular Screening Center
08/02/11
Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) (2K validation set)
The Scripps Research Institute Molecular Screening Center
08/02/11
SAR Analysis for the identification of selective inhibits of the transient receptor potential cation channel C4 (TRPC4): Automated Electrophysiology
Johns Hopkins Ion Channel Center
08/02/11
A confirmatory biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to quantify activity of synthesized compounds that inhibit the ATPase activity of Tag (3)
Southern Research Specialized Biocontainment Screening Center
08/01/11
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1
Nmmlsc
08/01/11
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically CIT2
Nmmlsc
08/01/11
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4
Nmmlsc
08/01/11
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically MEP2
Nmmlsc
08/01/11
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19A
Nmmlsc
08/01/11
Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2)
The Scripps Research Institute Molecular Screening Center
08/01/11
Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay - Set 2
Burnham Center For Chemical Genomics
08/01/11
Dose Response concentration confirmation of uHTS hits from a small molecule activators of mouse intestinal alkaline phosphatase via a luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of compounds that inhibit HePTP
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of inhibitors of NALP1 in yeast using a Caspase-1-ASC counter screen.
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of inhibitors of NALP3 in yeast using a Caspase-1-ASC counter screen
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Luminescent Interference Counterscreen assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS for the identification of inhibitors of NALP1 in yeast using a luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS for the identification of inhibitors of NALP3 in yeast using a luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS hits from a small molecule agonists of the APJ receptor via a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay - Set 2
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
Burnham Center For Chemical Genomics
08/01/11
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.
Burnham Center For Chemical Genomics
08/01/11
Dose Response screen for agonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule agonists hits of the APJ receptor
Burnham Center For Chemical Genomics
08/01/11
Dose Response: Fluorescence polarization-based cell-based high throughput dose response assay for inhibitors of insulin-degrading enzyme (IDE)
The Scripps Research Institute Molecular Screening Center
08/01/11
HTS Dose response counterscreen for assays utilizing the enzyme, beta-galactosidase - Set 2
Burnham Center For Chemical Genomics
08/01/11
Inhibitors of T-Type Calcium Channel
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
08/01/11
Late stage assay provider counterscreen results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): chemiluminescence-based western blot assay for inhibitors of KLF5 protein levels
The Scripps Research Institute Molecular Screening Center
08/01/11
Late-stage fluorescence dose response cell-based counterscreening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): inhibition by S1P4-selective antagonist
The Scripps Research Institute Molecular Screening Center
08/01/11
Late-stage fluorescence-based counterscreen for antagonists of the G-protein coupled receptor 7 (GPR7): cell-based dose response assay to identify antagonists of the melanin-concentrating hormone receptor 1 (MCHR1)
The Scripps Research Institute Molecular Screening Center
08/01/11
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
The Scripps Research Institute Molecular Screening Center
08/01/11
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7): Intracellular calcium release
The Scripps Research Institute Molecular Screening Center
08/01/11
SAR Analysis for the identification of Selective Antagonists of ERK1/2 Activity in GPR35-Overexpressing U2OS Cells
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis for the identification of Selective Antagonists of ERK1/2 Activity in GPR35-Overexpressing U2OS Cells - Set 2
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR Confirmatory Dose Response LIBS Assay for Allosteric Ligands of the VLA-4 Integrin
Nmmlsc
08/01/11
SAR LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR Selectivity Analysis of small molecule inhibitors of PEST using pCAP in a fluorescence assay
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay-Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of IAP-family anti-apoptotic proteins - Set 2
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of XIAP-Bir3 domain of IAP-family anti-apoptotic proteins - Set 2
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 5
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 6
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 5
Burnham Center For Chemical Genomics
08/01/11
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 6
Burnham Center For Chemical Genomics
08/01/11
TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
The Scripps Research Institute Molecular Screening Center
08/01/11
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R)
The Scripps Research Institute Molecular Screening Center
07/31/11
Counterscreen for vasopressin 1 receptor (V1R) agonists: Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR)
The Scripps Research Institute Molecular Screening Center
07/31/11
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator(PAM) : Activity with human M4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/31/11
Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay
Burnham Center For Chemical Genomics
07/31/11
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
Burnham Center For Chemical Genomics
07/31/11
Dose Response confirmation of uHTS hits from a small molecule inhibitors of LYP via a fluorescence intensity assay - Set 2
Burnham Center For Chemical Genomics
07/31/11
Dose Response confirmation of uHTS hits from a small molecule inhibitors of LYP via a fluorescence intensity assay using pCAP substrate
Burnham Center For Chemical Genomics
07/31/11
Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay
Burnham Center For Chemical Genomics
07/31/11
Dose Response of primary screening hit compounds for Identification of VLA-4 Allosteric Modulators
Nmmlsc
07/31/11
Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor
Burnham Center For Chemical Genomics
07/31/11
Fluorescence Cell-Free Homogeneous Counterscreen to Identify Inhibitors of the RanGTP-Importin-beta complex.
Broad Institute
07/31/11
Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction
Broad Institute
07/31/11
Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR)
The Scripps Research Institute Molecular Screening Center
07/31/11
Fluorescence-based cell-based high throughput dose response assay for potentiators of Oxytocin Receptor (OXTR)
The Scripps Research Institute Molecular Screening Center
07/31/11
Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R)
The Scripps Research Institute Molecular Screening Center
07/31/11
High throughput discovery of novel modulators of ROMK K+ channel activity: Analog Library Testing
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/31/11
High throughput fluorescence intensity-based biochemical assay to screen for small molecule inhibitors of Furin:Concentration-response Confirmation Assays
University of Pittsburgh
07/31/11
Late stage assay provider results from the probe development effort to identify inhibitors of GSTO1: Gel-based activity-based protein profiling (ABPP) IC50
The Scripps Research Institute Molecular Screening Center
07/31/11
Late stage assay provider results from the probe development effort to identify inhibitors of GSTO1: Gel-based activity-based protein profiling (ABPP) IC50 Set 2
The Scripps Research Institute Molecular Screening Center
07/31/11
Late stage assay provider results from the probe development effort to identify inhibitors of protein phosphatase methylesterase 1 (PME-1): Gel-based Activity-Based Protein Profiling (ABPP) IC50 Set 2
The Scripps Research Institute Molecular Screening Center
07/31/11
Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Family selectivity: Set 2
The Scripps Research Institute Molecular Screening Center
07/31/11
Late-stage fluorescence dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized compounds
The Scripps Research Institute Molecular Screening Center
07/31/11
Late-stage fluorescence-based dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Sphingosine 1-Phosphate Receptor 1 (S1P1) counterscreen assay
The Scripps Research Institute Molecular Screening Center
07/31/11
Late-stage fluorescence-based dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Sphingosine 1-Phosphate Receptor 2 (S1P2) counterscreen assay
The Scripps Research Institute Molecular Screening Center
07/31/11
Late-stage fluorescence-based dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Sphingosine 1-Phosphate Receptor 3 (S1P3) counterscreen assay
The Scripps Research Institute Molecular Screening Center
07/31/11
Late-stage fluorescence-based dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Sphingosine 1-Phosphate Receptor 5 (S1P5) counterscreen assay
The Scripps Research Institute Molecular Screening Center
07/31/11
Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR)
The Scripps Research Institute Molecular Screening Center
07/31/11
Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR)
The Scripps Research Institute Molecular Screening Center
07/31/11
Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/31/11
Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response with Rauwolscine
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/31/11
SAR LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies - Set 3
Burnham Center For Chemical Genomics
07/31/11
SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies - Set 3
Burnham Center For Chemical Genomics
07/31/11
SAR analysis for the identification of translation initiation inhibitors (PABP)
Burnham Center For Chemical Genomics
07/31/11
SAR analysis for the identification of translation initiation inhibitors (eIF4H)
Burnham Center For Chemical Genomics
07/31/11
SAR analysis of compounds that inhibit HePTP - Set 2
Burnham Center For Chemical Genomics
07/31/11
SAR analysis of compounds that inhibit Human Immunodeficiency Virus Fusion, cell-cell fusion assay
Burnham Center For Chemical Genomics
07/31/11
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
Burnham Center For Chemical Genomics
07/31/11
SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 3
Burnham Center For Chemical Genomics
07/31/11
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 4
Burnham Center For Chemical Genomics
07/31/11
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
The Scripps Research Institute Molecular Screening Center
07/30/11
Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation
Broad Institute
07/30/11
Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity
Broad Institute
07/30/11
Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase Set 2
The Scripps Research Institute Molecular Screening Center
07/30/11
Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50 Set 2
The Scripps Research Institute Molecular Screening Center
07/30/11
Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
The Scripps Research Institute Molecular Screening Center
07/30/11
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
Broad Institute
07/30/11
Luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Cherry picks 2
The Scripps Research Institute Molecular Screening Center
07/30/11
SAR analysis of compounds that inhibit Human Immunodeficiency Virus Fusion.
Burnham Center For Chemical Genomics
07/30/11
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 3
Burnham Center For Chemical Genomics
07/30/11
SAR analysis of small molecule inhibitors of Mint-PDZ and N-type Ca2+ channel carboxyl-terminal peptide association using HTRF - Set 2
Burnham Center For Chemical Genomics
07/30/11
Absorbance Microorganism Dose Response to Identify Inhibitors of Vibrio harveyi
Broad Institute
07/29/11
Fluorescence Cell-Based Secondary Assay of Resistant C. albicans Growth in the Presence of Fluconazole
Broad Institute
07/29/11
Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin
Broad Institute
07/29/11
Late stage counterscreen results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1): luminescence-based cell-based dose response assay for STAT3 activators
The Scripps Research Institute Molecular Screening Center
07/29/11
Late stage results from the probe development effort to identify activators of signal transducer and activator of transcription 1 (STAT1): luminescence-based cell-based dose response assay for STAT1 activators
The Scripps Research Institute Molecular Screening Center
07/29/11
Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
Broad Institute
07/29/11
Luminescence Cell-Free Homogeneous Dose Response to Identify Inhibitors of Lux-S
Broad Institute
07/29/11
Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity
Broad Institute
07/29/11
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
07/29/11
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4
Burnham Center For Chemical Genomics
07/29/11
SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/29/11
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3
Burnham Center For Chemical Genomics
07/29/11
SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/29/11
Dose Response confirmation of uHTS hits from a small molecule antagonists of the APJ receptor via a luminescent beta-arrestin assay
Sanford-Burnham Center For Chemical Genomics
07/12/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao with additional round of SAR compounds
Nmmlsc
07/12/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao with additional round of SAR compounds.
Nmmlsc
07/12/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao with additional round of SAR compounds.
Nmmlsc
07/12/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds
Nmmlsc
07/12/11
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
Emory University
07/12/11
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
The Scripps Research Institute Molecular Screening Center
07/12/11
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
The Scripps Research Institute Molecular Screening Center
07/12/11
Late stage results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT1 inhibitors
The Scripps Research Institute Molecular Screening Center
07/12/11
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs
The Scripps Research Institute Molecular Screening Center
07/12/11
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2
The Scripps Research Institute Molecular Screening Center
07/12/11
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 3
The Scripps Research Institute Molecular Screening Center
07/12/11
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
Broad Institute
07/12/11
SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2
Burnham Center For Chemical Genomics
07/12/11
SAR analysis of NF-kappaB dependent luciferase using Doxorucibin as an inducer - Set 2
Burnham Center For Chemical Genomics
07/12/11
SAR analysis of NF-kappaB dependent luciferase using PMA/Ionomycin as an inducer - 2
Burnham Center For Chemical Genomics
07/12/11
SAR analysis of compounds that inhibit NOD1 - Set 3
Burnham Center For Chemical Genomics
07/12/11
SAR analysis of compounds that inhibit NOD2 - Set 3
Burnham Center For Chemical Genomics
07/12/11
SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3
Burnham Center For Chemical Genomics
07/12/11
Absorbance Microorganism Dose Retest to Identify Inhibitors of Vibrio harveyi
Broad Institute
07/11/11
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression.
Broad Institute
07/11/11
Absorbance Microorganism-Based Dose Retest to Identify Inhibitors of Vibrio harveyi
Broad Institute
07/11/11
Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1
Johns Hopkins Ion Channel Center
07/11/11
Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): TR-FRET-based biochemical high throughput dose response assay to identify agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2)
The Scripps Research Institute Molecular Screening Center
07/11/11
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: PAM Calcium Assay SAR
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/11/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: PAM Calcium Assay Dose-Response with M3
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/11/11
Dosage response for compounds that protect hERG from block by proarrhythmic agents using manual patch clamp
Johns Hopkins Ion Channel Center
07/11/11
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits
Nmmlsc
07/11/11
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically CIT2 based on MLPCN hits
Nmmlsc
07/11/11
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits
Nmmlsc
07/11/11
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically MEP2 based on MLPCN hits
Nmmlsc
07/11/11
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
Nmmlsc
07/11/11
Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel
Johns Hopkins Ion Channel Center
07/11/11
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase
The Scripps Research Institute Molecular Screening Center
07/11/11
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase
The Scripps Research Institute Molecular Screening Center
07/11/11
Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase
The Scripps Research Institute Molecular Screening Center
07/11/11
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
University of Pittsburgh
07/11/11
HTS dose response assay for identification of inhibitors of TNFa-specific NF-kB induction
Burnham Center For Chemical Genomics
07/11/11
Late stage counterscreen for the probe development effort to identify selective agonists of the Transient Receptor Potential Channels 3 (TRPML3): fluorescence-based cell-based dose response assay for TRPN1 agonists.
The Scripps Research Institute Molecular Screening Center
07/11/11
Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase
The Scripps Research Institute Molecular Screening Center
07/11/11
Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50
The Scripps Research Institute Molecular Screening Center
07/11/11
Late stage results from the probe development effort to identify selective agonists of the Transient Receptor Potential Channels 3 (TRPML3): fluorescence-based cell-based dose response assay for TRPML3 agonists
The Scripps Research Institute Molecular Screening Center
07/11/11
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs
The Scripps Research Institute Molecular Screening Center
07/11/11
Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 2
The Scripps Research Institute Molecular Screening Center
07/11/11
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
Broad Institute
07/11/11
Luminescence Microorganism Dose Retest to Identify Inhibitors of the AI-2 Quorum Sensing System
Broad Institute
07/11/11
Luminescence Microorganism-Based Dose Retest to Identify Modulators of the AI-2 Quorum Sensing System
Broad Institute
07/11/11
Luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1)
The Scripps Research Institute Molecular Screening Center
07/11/11
Mode of action - deactivation constant concentration response for ztz240, a potentiator of KCNQ2 potassium channels
Johns Hopkins Ion Channel Center
07/11/11
Mode of action assay-Automated electrophysiology assay of compounds that potentiate KCNQ2 potassium channel
Johns Hopkins Ion Channel Center
07/11/11
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of Muramyl dipeptide (MDP) induced IL-8 secretion in MCF-7/NOD2 cells - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of Tumor necrosis factor alpha (TNF-alpha) induced IL-8 secretion in MCF-7/NOD1 cells - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of compounds that inhibit NOD1 - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of compounds that inhibit NOD2 - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay - Set 2
Burnham Center For Chemical Genomics
07/11/11
SAR analysis of small molecule inhibitors of Mint-PDZ and N-type Ca2+ channel carboxyl-terminal peptide association using HTRF
Burnham Center For Chemical Genomics
07/11/11
TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)
The Scripps Research Institute Molecular Screening Center
07/11/11
Counterscreen for inhibitors of EBNA-1: fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of the Epstein-Barr virus-encoded protein, ZTA
The Scripps Research Institute Molecular Screening Center
07/10/11
Counterscreen for inhibitors of PP1: fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 5 (PP5)
The Scripps Research Institute Molecular Screening Center
07/10/11
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 1 (PP1)
The Scripps Research Institute Molecular Screening Center
07/10/11
Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole
Broad Institute
07/10/11
Fluorescence Cell-Based Secondary Assay to Measure Toxicity of Compounds Not in the Presence of Fluconazole
Broad Institute
07/10/11
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)
The Scripps Research Institute Molecular Screening Center
07/10/11
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
The Scripps Research Institute Molecular Screening Center
07/10/11
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1)
The Scripps Research Institute Molecular Screening Center
07/10/11
HTS Image-Based Screen for Agonists of the DOR Receptor
Burnham Center For Chemical Genomics
07/10/11
HTS Image-Based Screen for Antagonists of the DOR Receptor
Burnham Center For Chemical Genomics
07/10/11
Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 1 (S1P1)
The Scripps Research Institute Molecular Screening Center
07/10/11
Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 2 (S1P2)
The Scripps Research Institute Molecular Screening Center
07/10/11
Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 3 (S1P3)
The Scripps Research Institute Molecular Screening Center
07/10/11
Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5)
The Scripps Research Institute Molecular Screening Center
07/10/11
Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized analogues
The Scripps Research Institute Molecular Screening Center
07/10/11
Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
Broad Institute
07/10/11
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin
Broad Institute
07/10/11
Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90
Broad Institute
07/10/11
Mode of action - current amplitude concentration response for ztz240, a potentiator of KCNQ2 potassium channels
Johns Hopkins Ion Channel Center
07/10/11
SAR Analysis of Agonists of the DOR Receptor using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR analysis of Agonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
SAR analysis of Antagonists of the Kappa Opioid Receptor (KOR) using an Image-Based Assay
Burnham Center For Chemical Genomics
07/10/11
Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series
University of Pittsburgh
07/09/11
Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
The Scripps Research Institute Molecular Screening Center
07/09/11
Counterscreen for inhibitors of MCL1: fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of BCL2-related protein, long isoform (BCLXL).
The Scripps Research Institute Molecular Screening Center
07/09/11
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
07/09/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds
Nmmlsc
07/09/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao for SAR Compounds
Nmmlsc
07/09/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds
Nmmlsc
07/09/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao for SAR Compounds
Nmmlsc
07/09/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao for SAR Compounds
Nmmlsc
07/09/11
Fluorescence counterscreen for potentiators or agonists of NPY-Y1: Cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based counterscreen for potentiators or agonists of NPY-Y2: cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y1.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
The Scripps Research Institute Molecular Screening Center
07/09/11
Fluorescence-based dose response cell-based high-throughput screening assay for potentiators or agonists of NPY-Y1.
The Scripps Research Institute Molecular Screening Center
07/09/11
Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay
Burnham Center For Chemical Genomics
07/09/11
Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
Southern Research Specialized Biocontainment Screening Center
07/09/11
Image-Based HTS for Selective Antagonists for GPR55
Burnham Center For Chemical Genomics
07/09/11
Image-Based HTS for Selective Antagonists of GPR35
Burnham Center For Chemical Genomics
07/09/11
Image-based HTS for Selective Agonists of GPR55
Burnham Center For Chemical Genomics
07/09/11
Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)
The Scripps Research Institute Molecular Screening Center
07/09/11
SAR analysis of NF-kB dependent luciferase using DAP as an inducer
Burnham Center For Chemical Genomics
07/09/11
SAR analysis of compounds that inhibit NOD1 revised
Burnham Center For Chemical Genomics
07/09/11
SAR analysis of compounds that inhibit NOD2 revised
Burnham Center For Chemical Genomics
07/09/11
SAR analysis of inhibitors of TNFa specific NF-kB induction revised
Burnham Center For Chemical Genomics
07/09/11
SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
07/09/11
SAR analysis of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
07/09/11
uHTS HTRF assay for identification of inhibitors of SUMOylation
Burnham Center For Chemical Genomics
07/09/11
uHTS absorbance assay for the identification of compounds that inhibit VHR1.
Burnham Center For Chemical Genomics
07/09/11
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)
Burnham Center For Chemical Genomics
07/09/11
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
Burnham Center For Chemical Genomics
07/09/11
uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay.
Burnham Center For Chemical Genomics
07/09/11
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
Burnham Center For Chemical Genomics
07/09/11
uHTS identification of small molecule inhibitors of LYP via a fluorescence intensity assay
Burnham Center For Chemical Genomics
07/09/11
Chemical Antagonists IAP-family anti-apoptotic proteins
Sanford-Burnham Center For Chemical Genomics
07/08/11
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
Srmlsc
07/08/11
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
Burnham Center For Chemical Genomics
07/08/11
uHTS identification of compounds activating TNAP in the absence of phosphate acceptor performed in luminescent assay
Sanford-Burnham Center For Chemical Genomics
07/08/11
uHTS luminescence assay for the identification of compounds that inhibit NOD1
Burnham Center For Chemical Genomics
07/08/11
Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits
Southern Research Specialized Biocontainment Screening Center
06/09/11
Oxadiazole SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
Nmmlsc
06/09/11
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
Broad Institute
06/08/11
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
Emory University
06/07/11
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
Broad Institute
06/05/11
Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
Nmmlsc
06/05/11
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Nmmlsc
06/05/11
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
Burnham Center For Chemical Genomics
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2
Nmmlsc
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B
Nmmlsc
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
Nmmlsc
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL
Nmmlsc
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1
Nmmlsc
06/05/11
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1
Nmmlsc
06/05/11
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
The Scripps Research Institute Molecular Screening Center
06/05/11
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Fold-shift Assay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: [3H]N-methylscopolamine Competition
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: [3H]N-methylscopolamine Competition with Acetylcholine
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Dose Response of SAR compounds via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Wildtype
Nmmlsc
06/05/11
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
The Scripps Research Institute Molecular Screening Center
06/05/11
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3).
The Scripps Research Institute Molecular Screening Center
06/05/11
HTS TR-FRET-based dose response confirmatory assay for Siah-1
Burnham Center For Chemical Genomics
06/05/11
HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies
Burnham Center For Chemical Genomics
06/05/11
HTS Image-Based Screen for Selective Agonists of the KOR Receptor
Burnham Center For Chemical Genomics
06/05/11
HTS Image-Based Screen for Selective Antagonists of the KOR Receptor
Burnham Center For Chemical Genomics
06/05/11
HTS fluorescence polarization-based dose response confirmatory screen for the Siah-1 primary assay utilizing an alternative fluorophore, fluorescein-labeled plectin
Burnham Center For Chemical Genomics
06/05/11
LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies.
Burnham Center For Chemical Genomics
06/05/11
MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
Burnham Center For Chemical Genomics
06/05/11
MOA VHR1 Fluorescent secondary assay for identification of redox-state modulating compounds
Burnham Center For Chemical Genomics
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Potency at human mGluR4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Rat PAM Potency
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR1
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR2
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR3
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR5
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR6
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR7
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Modulation of the Metabotropic Glutamate Receptor mGluR4: Selectivity at mGluR8
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
Nmmlsc
06/05/11
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype protein
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
Nmmlsc
06/05/11
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Nmmlsc
06/05/11
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP).
The Scripps Research Institute Molecular Screening Center
06/05/11
QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
The Scripps Research Institute Molecular Screening Center
06/05/11
SAR Compounds tested by Dose Response Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Mutant.
Nmmlsc
06/05/11
SAR Compounds tested by Dose Response Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 3 Wildtype.
Nmmlsc
06/05/11
SAR LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies
Burnham Center For Chemical Genomics
06/05/11
SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies
Burnham Center For Chemical Genomics
06/05/11
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
The Scripps Research Institute Molecular Screening Center
06/05/11
uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay
Burnham Center For Chemical Genomics
06/05/11
uHTS luminescence assay for the identification of compounds that inhibit NOD2 in MDP treated cells
Burnham Center For Chemical Genomics
06/05/11
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
Burnham Center For Chemical Genomics
06/04/11
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
Sanford-Burnham Center For Chemical Genomics
06/04/11
High Throughput Screening Assay for Hsc70 Inhibitors
Burnham Center For Chemical Genomics
06/04/11
Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP)
Srmlsc
06/04/11
Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
The Scripps Research Institute Molecular Screening Center
06/01/11
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
The Scripps Research Institute Molecular Screening Center
06/01/11
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
The Scripps Research Institute Molecular Screening Center
06/01/11
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
The Scripps Research Institute Molecular Screening Center
06/01/11
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
Broad Institute
06/01/11
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
Broad Institute
06/01/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS competition at M3
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/31/11
Dose Response Confirmation Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Mutant
Nmmlsc
05/31/11
Dose Response Confirmation via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Wildtype
Nmmlsc
05/31/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
Nmmlsc
05/31/11
Fluorescence counterscreen assay for TRPML3 agonists: dose response cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel N1 (TRPN1)
The Scripps Research Institute Molecular Screening Center
05/31/11
Fluorescence counterscreen assay for TRPN1 agonists: dose response cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel ML3 (TRPML3)
The Scripps Research Institute Molecular Screening Center
05/31/11
Fluorescent assay for identification of compounds that inhibit VHR1
Burnham Center For Chemical Genomics
05/31/11
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Dose-Dependent Assay 2 with KCC2
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/31/11
SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay
Burnham Center For Chemical Genomics
05/31/11
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/30/11
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/30/11
Dose Response Confirmation for Small Molecule Inhibitors of Epstein-Barr Virus
Emory University
05/30/11
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation
Emory University
05/30/11
Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation
Emory University
05/30/11
Estrogen Receptor-beta Coactivator Binding Inhibitors ELISA Secondary Assay
Emory University
05/30/11
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
Sanford-Burnham Center For Chemical Genomics
05/30/11
Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
Srmlsc
05/30/11
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator (PAM): Analog Dose Response with rM4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator (PAM): NMS Competition at rM4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Discovery of a Highly Selective in vitro and in vivo M4 Positive Allosteric Modulator(PAM): Analog Potency
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS competition at M2
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS competition at M4
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Dose Response for ABC transporter inhibitors: specifically ABCG2 screen, ABCB1 counter-screen
Nmmlsc
05/29/11
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
Nmmlsc
05/29/11
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
Nmmlsc
05/29/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
Nmmlsc
05/29/11
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
Nmmlsc
05/29/11
Fluorescence-based counterscreen assay for S1P4 agonists: Cell-based dose response high throughput screening assay to identify agonists of the Sphingosine 1-Phosphate Receptor 1 (S1P1)
The Scripps Research Institute Molecular Screening Center
05/29/11
HTS Dose response counterscreen for assays utilizing the enzyme, b-galactosidase
Burnham Center For Chemical Genomics
05/29/11
Identification of Novel Modulators of Cl- dependent Transport Process via HTS; Dose-dependent Assay with KCC2
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/29/11
Luminescence-based dose response biochemical high throughput screening assay for inhibitors of the Heat Shock Protein 90 (HSP90)
The Scripps Research Institute Molecular Screening Center
05/29/11
Luminescent counterscreen for inhibitors of the Janus kinase 2 mutant JAK2V617F: dose response cell-based high throughput screening assay for inhibitors of parental Ba/F3 cell viability.
The Scripps Research Institute Molecular Screening Center
05/29/11
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
Nmmlsc
05/29/11
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
The Scripps Research Institute Molecular Screening Center
05/29/11
SAR VHR1 Fluorescent Assay for In Vitro dose response studies
Burnham Center For Chemical Genomics
05/29/11
SAR VHR1 absorbance Assay for In Vitro dose response studies.
Burnham Center For Chemical Genomics
05/29/11
SAR assay for compounds inhibiting TNAP in the absence of phosphate acceptor performed in a luminescent assay
Burnham Center For Chemical Genomics
05/29/11
Concentration Response Redox Cycling H2O2 Generation assay, 1 mM DTT, to characterize small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS.
University of Pittsburgh
05/28/11
Concentration Response fluorescence polarization-based assay to test PMLSC Chemistry Core synthesized analogs of confirmed hits from the Polo box domain (PBD) of Plk1 Primary HTS.
University of Pittsburgh
05/28/11
Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate.
Burnham Center For Chemical Genomics
05/28/11
Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
Burnham Center For Chemical Genomics
05/28/11
Counter Screen using XIAP-Bir3 of the Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation assay
Burnham Center For Chemical Genomics
05/28/11
Counter screen SAR assay for PMM2 inhibitors via a fluorescence intensity assay
Burnham Center For Chemical Genomics
05/28/11
Counterscreen assay for PERK inhibitors: Dose response cell-based high throughput screening assay to measure inhibition of PERK at 6 hours
The Scripps Research Institute Molecular Screening Center
05/28/11
Counterscreen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA: S1P2 Purchased Analogues
The Scripps Research Institute Molecular Screening Center
05/28/11
Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
The Scripps Research Institute Molecular Screening Center
05/28/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS binding at M1
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/28/11
Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response cell-based assay to measure STAT3 inhibition
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response cell-based high throughput screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 3 (S1P3)
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel N1 (TRPN1)
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response cell-based high-throughput screening assay to measure PERK inhibition
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response counterscreen assay for STAT3 inhibitors: cell-based high throughput assay to measure STAT1 inhibition
The Scripps Research Institute Molecular Screening Center
05/28/11
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
The Scripps Research Institute Molecular Screening Center
05/28/11
Fluorescence polarization assay for PKD inhibitiors-interference assay-57K HTS campaign
University of Pittsburgh
05/28/11
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
Burnham Center For Chemical Genomics
05/28/11
HTS assay for inhibitors of Trypanosoma brucei hexokinase 1: IC50 determinations
University of Pittsburgh
05/28/11
In Vitro Hsc70 Dose Response Fluorescence Polarization Assay
Sanford-Burnham Center For Chemical Genomics
05/28/11
Luminescence counterscreen assay for p97 inhibitors: Dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase.
The Scripps Research Institute Molecular Screening Center
05/28/11
Luminescence counterscreen assay for p97 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase: synthesized compounds.
The Scripps Research Institute Molecular Screening Center
05/28/11
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation
Burnham Center For Chemical Genomics
05/28/11
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
Nmmlsc
05/28/11
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype
Nmmlsc
05/28/11
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
Nmmlsc
05/28/11
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
Nmmlsc
05/28/11
SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay
Burnham Center For Chemical Genomics
05/28/11
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC - Secondary Assay
Srmlsc
05/28/11
TR-FRET counterscreen for FAK inhibitors: dose-response biochemical high throughput screening assay to identify inhibitors of Proline-rich tyrosine kinase 2 (Pyk2)
The Scripps Research Institute Molecular Screening Center
05/28/11
Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists
Sanford-Burnham Center For Chemical Genomics
05/27/11
Counter Screen for Placental Alkaline Phosphatase-based Assays Positives
Burnham Center For Chemical Genomics
05/27/11
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
The Scripps Research Institute Molecular Screening Center
05/27/11
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
The Scripps Research Institute Molecular Screening Center
05/27/11
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist Activity against Muscarinic Panel
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/25/11
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Rubidium Flux
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
05/25/11
SAR analysis of Antagonists of IAP-family anti-apoptotic proteins
Burnham Center For Chemical Genomics
05/25/11
SAR analysis of Antagonists of XIAP-Bir3 domain of IAP-family anti-apoptotic proteins
Burnham Center For Chemical Genomics
05/25/11
SAR analysis of compounds that potentiate TRAIL-induced apoptosis in MDA-MB-435 cells.
Burnham Center For Chemical Genomics
05/25/11
SAR analysis of compounds that potentiate TRAIL-induced apoptosis in PPC-1 cells.
Burnham Center For Chemical Genomics
05/25/11
CDK7 counterscreen of confirmed PKD inhibitors-57K library addition
University of Pittsburgh
05/21/11
Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation
Burnham Center For Chemical Genomics
05/21/11
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
The Scripps Research Institute Molecular Screening Center
05/21/11
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
The Scripps Research Institute Molecular Screening Center
05/21/11
Dose response cell-based assay to measure STAT1 inhibition
The Scripps Research Institute Molecular Screening Center
05/21/11
Dose response cell-based assay to measure STAT3 activation
The Scripps Research Institute Molecular Screening Center
05/21/11
Dose response counterscreen assay for STAT3 activators: cell-based high throughput assay to measure STAT1 activation
The Scripps Research Institute Molecular Screening Center
05/21/11
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
The Scripps Research Institute Molecular Screening Center
05/21/11
SAR assay for compounds activating TNAP in the absence of phosphate acceptor performed in a luminescent assay
Burnham Center For Chemical Genomics
05/21/11
Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)
The Scripps Research Institute Molecular Screening Center
05/20/11
Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3)
The Scripps Research Institute Molecular Screening Center
05/20/11
Dose response cell-based high throughput screening assay to identify enhancers of beta-glucosidase activity
The Scripps Research Institute Molecular Screening Center
05/20/11
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
The Scripps Research Institute Molecular Screening Center
05/20/11
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
The Scripps Research Institute Molecular Screening Center
05/20/11
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
The Scripps Research Institute Molecular Screening Center
05/20/11
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
Nmmlsc
05/20/11
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Nmmlsc
05/20/11
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
Nmmlsc
05/20/11
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1.
Nmmlsc
05/20/11
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
Nmmlsc
05/20/11
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2
Nmmlsc
05/20/11
Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)
Ncgc
05/17/11
Counter Screen for TR3-Based Bcl-B Inhibitors: Fluorescence Polarization Bcl-B/FITC-Bim-BH3 Assay
Sanford-Burnham Center For Chemical Genomics
05/17/11
Dose Response cell-based high-throughput screening assay to identify agonists of galanin receptor 2 (GALR2)
The Scripps Research Institute Molecular Screening Center
05/17/11
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
The Scripps Research Institute Molecular Screening Center
05/17/11
Dose response counterscreen for agonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for activators of beta-lactamase activity
The Scripps Research Institute Molecular Screening Center
05/17/11
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
The Scripps Research Institute Molecular Screening Center
05/17/11
Estrogen Receptor-alpha Coactivator Binding Inhibitors ELISA Secondary Assay
Emory University
05/17/11
Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors
Sanford-Burnham Center For Chemical Genomics
05/17/11
GAPDH Dose Response Colorimetric Assay
Sanford-Burnham Center For Chemical Genomics
05/17/11
High Throughput Screen to Identify Compounds that Inhibit Class II HMG-CoA Reductases - Confirmatory Screen
Srmlsc
05/17/11
In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
Sanford-Burnham Center For Chemical Genomics
05/17/11
In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study
Burnham Center For Chemical Genomics
05/17/11
Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase
Sanford-Burnham Center For Chemical Genomics
05/17/11
MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors
Burnham Center For Chemical Genomics
05/17/11
SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation
Emory University
05/17/11
sEH_DR_Inh_Infinite200_Fluorescence_01072008
Columbia University Molecular Screening Center
05/17/11
Concentration Response Redox Cycling H2O2 Generation assay to characterize small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS.
University of Pittsburgh
05/12/11
Concentration Response fluorescence polarization-based assay to confirm small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS.
University of Pittsburgh
05/12/11
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor
The Scripps Research Institute Molecular Screening Center
05/12/11
Dose Response Cell Based Assay for Agonists of the S1P2 Receptor of Purchased Analogues
The Scripps Research Institute Molecular Screening Center
05/12/11
Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor
The Scripps Research Institute Molecular Screening Center
05/12/11
Dose-response biochemical assay for antagonists of the interaction between the Eph receptor B4 (EphB4) and its ligand ephrin-B2 via TNYL-RAW peptide
The Scripps Research Institute Molecular Screening Center
05/12/11
Dose-response biochemical assay for inhibitors of Focal Adhesion Kinase (FAK)
The Scripps Research Institute Molecular Screening Center
05/11/11
TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70
Burnham Center For Chemical Genomics
05/11/11
Cell-based secondary assay for identifying Hsp90 inhibitors that degrade Hsp90 client protein Her2
Emory University
05/06/11
Dose response biochemical assay for autofluorescent inhibitors of Matrix Metalloproteinase 13 (MMP13) activity
The Scripps Research Institute Molecular Screening Center
05/06/11
Dose-response biochemical assay for inhibitors of Matrix Metalloproteinase 13 (MMP13) activity
The Scripps Research Institute Molecular Screening Center
05/06/11
Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation
Emory University
05/06/11
Estrogen Receptor-alpha Coactivator Binding Potentiators Dose Response Confirmation
Emory University
05/06/11
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Nmmlsc
05/06/11
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
Nmmlsc
05/06/11
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay
Nmmlsc
05/06/11
Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : FPR Dose Response Counterscreen Assay
Nmmlsc
05/06/11
High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters
Burnham Center For Chemical Genomics
05/06/11
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Agonists
The Scripps Research Institute Molecular Screening Center
05/06/11
S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E Antagonists
The Scripps Research Institute Molecular Screening Center
05/06/11
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
The Scripps Research Institute Molecular Screening Center
05/04/11
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
The Scripps Research Institute Molecular Screening Center
05/04/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response Reproducibility Assay
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response assay in 25 mM DTT
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response assay in 25 mM DTT and Catalase.
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response assay in the presence of Beta-Mercaptoethanol.
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response assay in the presence of Catalase.
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment Dose Response assay in the presence of Glutathione.
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison.
University of Pittsburgh
04/30/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-3 Dose Response Selectivity comparison.
University of Pittsburgh
04/30/11
Counterscreen for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA)
The Scripps Research Institute Molecular Screening Center
04/30/11
Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
The Scripps Research Institute Molecular Screening Center
04/30/11
Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA)
The Scripps Research Institute Molecular Screening Center
04/30/11
Dose-response biochemical assay of inhibitors of Rho kinase 2 (Rock2)
The Scripps Research Institute Molecular Screening Center
04/30/11
Dose-response cell-based assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)
The Scripps Research Institute Molecular Screening Center
04/30/11
Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)
The Scripps Research Institute Molecular Screening Center
04/30/11
Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1)
The Scripps Research Institute Molecular Screening Center
04/30/11
HTS for LYP Inhibitors-an Autoimmunity Target - Primary screen
Columbia University Molecular Screening Center
04/30/11
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase
University of Pittsburgh
04/30/11
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of DTT
University of Pittsburgh
04/30/11
In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
University of Pittsburgh
04/30/11
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Effects of Catalase
University of Pittsburgh
04/30/11
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
University of Pittsburgh
04/30/11
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase
Burnham Center For Chemical Genomics
04/30/11
MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment: Cdc25B Dose Response Selectivity Assay
University of Pittsburgh
04/30/11
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
Srmlsc
04/30/11
TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
Sanford-Burnham Center For Chemical Genomics
04/30/11
West Nile Virus NS2bNS3 Proteinase Inhibitor Dose Response Confirmation.
University of Pittsburgh
04/30/11
Clearance of Mutant Huntingtin Protein - Confirmatory screen
Columbia University Molecular Screening Center
04/29/11
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Nmmlsc
04/29/11
Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands
Nmmlsc
04/29/11
Dose Response Assay for S1P3 Antagonists
The Scripps Research Institute Molecular Screening Center
04/29/11
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR
The Scripps Research Institute Molecular Screening Center
04/29/11
Dose-response biochemical assay for inhibitors of protein kinase A (PKA) activity
The Scripps Research Institute Molecular Screening Center
04/29/11
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
University of Pittsburgh
04/29/11
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
Srmlsc
04/29/11
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay
University of Pittsburgh
04/28/11
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
The Scripps Research Institute Molecular Screening Center
04/28/11
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR
The Scripps Research Institute Molecular Screening Center
04/28/11
In vitro MKP-1 Phosphatase Dose Response Confirmation and Secondary Selectivity/Specificity Assay
University of Pittsburgh
04/28/11
In vitro MKP-3 Phosphatase Dose Response Confirmation and Secondary Selectivity/Selectivity Assay
University of Pittsburgh
04/28/11
S1P3 Agonist Dose-Response Potency Assay
The Scripps Research Institute Molecular Screening Center
04/28/11
In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay
University of Pittsburgh
12/17/09
HIV-1 RT-RNase H MLSCN MH077605 Probe Assessment: Dose response Assay
University of Pittsburgh
11/24/09
HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
Burnham Center For Chemical Genomics
11/24/09
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate
Burnham Center For Chemical Genomics
11/24/09
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1.
Nmmlsc
10/26/09
Fluorescence polarization assay for PKD inhibitiors-IC50 determinations
University of Pittsburgh
10/09/09
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL.
Nmmlsc
10/09/09
High Throughput Screening Assay for Hsp70 Inhibitors
Burnham Center For Chemical Genomics
09/25/09
In Vitro MKP-3 Dose Response Assay for SAR Study
Burnham Center For Chemical Genomics
09/25/09
Counterscreen assay for S1P3 antagonists: Dose response cell-based high throughput screening assay to identify antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
The Scripps Research Institute Molecular Screening Center
09/05/09
Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
The Scripps Research Institute Molecular Screening Center
09/05/09
Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
The Scripps Research Institute Molecular Screening Center
09/05/09
Dose Response Assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) Agonists
The Scripps Research Institute Molecular Screening Center
08/14/09
Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1A (5HT1A)
The Scripps Research Institute Molecular Screening Center
08/14/09
Dose Response assay for agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
The Scripps Research Institute Molecular Screening Center
08/14/09
Confirmation of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay
Burnham Center For Chemical Genomics
07/24/09
Confirmation of compounds inhibiting the binding between the RUNX1 Runt domain and CBFbeta-SMMHC via a time resolved fluorescence resonance energy transfer (TR-FRET) assay.
Burnham Center For Chemical Genomics
07/24/09
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFbeta-SMMHC via a fluorescence resonance energy transfer (FRET) assay.
Burnham Center For Chemical Genomics
07/24/09
Identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a time resolved fluorescence resonance energy transfer (TR-FRET) assay.
Burnham Center For Chemical Genomics
06/18/09