Binding Database

BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,359K data for 631K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

Unveiling the Structure-Activity Relationships at the Orthosteric Binding Site of P2X Ion Channels: The Route to Selectivity.

European Institute For Molecular Imaging (Eimi)

Discovery of 5-methyl-1H-benzo[d]imidazole derivatives as novel P2X3 Receptor antagonists.

Gwangju Institute of Science and Technology (Gist)

Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2

National Institute of Diabetes and Digestive and Kidney Diseases

Dioxotriazine derivatives as a new class of P2X

Shionogi

New P2X3 receptor antagonists. Part 1: Discovery and optimization of tricyclic compounds.

Gedeon Richter

Novel Series of Dihydropyridinone P2X7 Receptor Antagonists.

Hoffmann-La Roche

Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening.

Shionogi