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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.EBI
Lexicon Pharmaceuticals
4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.EBI
Lexicon Pharmaceuticals
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.EBI
University College London
Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling.EBI
University College London
Fragment-to-Lead Medicinal Chemistry Publications in 2020.EBI
Vrije Universiteit Amsterdam
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.EBI
University College London
Structural Insights into Notum Covalent Inhibition.EBI
University of Oxford
5-Phenyl-1,3,4-oxadiazol-2(3EBI
University College London
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.EBI
University College London
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors.EBI
University College London
Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling.EBI
The Scripps Research Institute