PMID

Data

Article Title

Organization

2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.

Palacky University In Olomouc

Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639.

Abbvie

Synthesis and biological evaluation of 2,3'-diindolylmethanes as agonists of aryl hydrocarbon receptor.

University of Wisconsin

Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor.

University of Utah

8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.

University of Bonn

Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.

Harvard University

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

University of Oxford

Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.

University of Maryland

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

Cnrs

Imidazo[1,5-a]quinoxalines as irreversible BTK inhibitors for the treatment of rheumatoid arthritis.

Pfizer

Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry.

The University of Tokyo

beta-Naphthoflavone analogs as potent and soluble aryl hydrocarbon receptor agonists: improvement of solubility by disruption of molecular planarity.

The University of Tokyo

Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).

Cardiff University

Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.

Palack£

Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.

Sichuan University

The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.

Max Planck Institute of Molecular Physiology

Structural modification aimed for improving solubility of lead compounds in early phase drug discovery.

Indian Institute of Technology (B.H.U.)

An electrochemical device for the assay of the interaction between a dioxin receptor and its various ligands.

Kyushu University

Indole scaffolds as a promising class of the aryl hydrocarbon receptor ligands.

Palack£

Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes.

Universitat De Val£Ncia. Av. Vicente Andr£S Estell£S

Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor.

University of Wisconsin-Madison

Development of Chemical Entities Endowed with Potent Fast-Killing Properties against

Glaxosmithkline

Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model.

Gwangju Institute of Science and Technology

Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs).

University of Perugia

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17?-Hydroxysteroid Dehydrogenase Type 2.

University of Basel

Synthesis and biological evaluation of pyrrole-based chalcones as CYP1 enzyme inhibitors, for possible prevention of cancer and overcoming cisplatin resistance.

De Montfort University

Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites.

Mcgill University