20 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Selective Inhibitors of Human Liver Carboxylesterase Based on aß-Lapachone Scaffold: Novel Reagents for Reaction Profiling.
St. Jude Children'S Research Hospital
Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2.
Dalian Institute of Chemical Physics
Protostane Triterpenoids from the Rhizome of Alisma orientale Exhibit Inhibitory Effects on Human Carboxylesterase 2.
Liaoning University of Traditional Chinese Medicine
Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver.
Kanazawa University
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").
St. Jude Children'S Research Hospital
Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors.
University of California
Isosorbide-2-benzyl carbamate-5-salicylate, a peripheral anionic site binding subnanomolar selective butyrylcholinesterase inhibitor.
Trinity College
Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH).
University of California
Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones.
St. Jude Children'S Research Hospital
Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils.
St. Jude Children'S Research Hospital
Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety.
St. Jude Children'S Research Hospital
Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells.
Shanghai University of Traditional Chinese Medicine
Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold.
Institute of Physiologically Active Compounds Russian Academy of Sciences
Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors.
Shanghai University of Traditional Chinese Medicine
Bioactivity-Guided Discovery of Human Carboxylesterase Inhibitors from the Roots of
Chinese Academy of Medical Sciences and Peking Union Medical College
Discovery of heterocyclic carbohydrazide derivatives as novel selective fatty acid amide hydrolase inhibitors: design, synthesis and anti-neuroinflammatory evaluation.
China Pharmaceutical University
Yanhusanines A-F, Isoquinoline-Derived Alkaloid Enantiomers from
Chinese Academy of Medical Sciences and Peking Union Medical College
Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.
University of California Davis