BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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11 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors.EBI
Insilico Medicine Shanghai Ltd
Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient Tumors.EBI
China Pharmaceutical University
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives.EBI
University of Bologna
Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy.EBI
University of Perugia
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.EBI
Artios Pharma
Identification of EBI
Repare Therapeutics
N-(PYRROLIDIN-3-YL OR PIPERIDIN-4-YL)ACETAMIDE DERIVATIVESBDB
Takeda Pharmaceutical
HETEROARYL DERIVATIVE AND USES THEREOFBDB
Iucf-Hyu
N-(4-aminocyclohexyl)pyrimidine-4-carboxamide derivatives as CD38 inhibitorsBDB
Cerevance
MEDICINE FOR PREVENTION AND TREATMENT OF DISEASES LINKED TO ANTI-OBESITY ACTIVITYBDB
Shionogi
METHODS OF TREATING MOOD DISORDERSBDB
Gilgamesh Pharmaceuticals