27 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
14
Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.
Cellzome
118
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
University of Oxford
2
In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase.
Martin-Luther-University Halle-Wittenberg
10
Substituted N-aryl-6-pyrimidinones: a new class of potent, selective, and orally active p38 MAP kinase inhibitors.
Pfizer
7
AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).
Ambit Biosciences
6
Novel Indazole Compounds as PKMYT1 Kinase Inhibitors for Treating Cancer.
Smith, Gambrell & Russell
39
Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy.
China Innovation Center of Roche
14
Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer.
Insilico Medicine Shanghai Ltd
43
Targeting Protein Kinase, Membrane-Associated Tyrosine/Threonine 1 (PKMYT1) for Precision Cancer Therapy: From Discovery to Clinical Trial.
China Pharmaceutical University
8
Structure-based virtual screening discovers novel PKMYT1 inhibitors.
Shenyang Pharmaceutical University
1
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
Eli Lilly
3
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
Johann Wolfgang Goethe University
3
Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1-Amplified Breast Cancer.
Jinan University
52
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Repare Therapeutics
20
A small molecule-kinase interaction map for clinical kinase inhibitors.
Ambit Biosciences
23
Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1.
Martin-Luther-University Halle-Wittenberg
18
Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II.
Martin-Luther-University Halle-Wittenberg
11
Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors.
Moffitt Cancer Center
11
USE OF HPK1 INHIBITOR IN TREATMENT OF INTERFERON-RELATED DISEASES
Asclepieion Pharmaceutical
20
4-(2-PYRAZOLO[3,4-B]PYRIDINE-5-YL)ETHYNYL-2-PYRIDINE DERIVATIVES USEFUL AS GCN2 INHIBITORS
IP2IPO Innovations
81
Heterocyclic compounds as class II phosphoinositide 3-kinase inhibitors
Forschungsverbund Berlin
147
Cyanopyrrolidines as dub inhibitors for the treatment of cancer
Mission Therapeutics