BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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5 articles for JE Souness

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency.EBI
Aventis Pharma
Quaternary substituted PDE4 inhibitors I: the synthesis and in vitro evaluation of a novel series of oxindoles.EBI
Rh£Ne-Poulenc Rorer Central Research
Mapping the kinase domain of Janus Kinase 3.EBI
Aventis Pharmaceuticals
Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.EBI
RhôNe-Poulenc Rorer
An algorithm-directed two-component library synthesized via solid-phase methodology yielding potent and orally bioavailable p38 MAP kinase inhibitors.EBI
Aventis Pharma