The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Chiral 6-aryl-furo[2,3-d]pyrimidin-4-amines as EGFR inhibitors.EBI
Norwegian University of Science and Technology
Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties.EBI
Norwegian University of Science and Technology
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors.EBI
Norwegian University of Science and Technology
Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines.EBI
Norwegian University of Science and Technology
Pyrrolopyrimidine based CSF1R inhibitors: Attempted departure from Flatland.EBI
Norwegian University of Science and Technology
Synthesis and Development of Highly Selective Pyrrolo[2,3-EBI
Norwegian University of Science and Technology
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors.EBI
Norwegian University of Science and Technology
Identification of fused pyrimidines as interleukin 17 secretion inhibitors.EBI
Norwegian University of Science and Technology
Small molecule inhibitors of ULK1BDB
Memorial Sloan Kettering Cancer Center
Biphenyl fluorine double bond derivative, preparation method therefor, and pharmaceutical application thereofBDB
Abbisko Therapeutics Co.