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BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 765K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
14
Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the Plasmodium falciparum dUTPase.EBI
University of Dundee
9
Site-directed mutagenesis provides insights into the selective binding of trityl derivatives to Plasmodium falciparum dUTPase.EBI
Instituto De Parasitolog£A Y Biomedicina L£Pez-Neyra
28
1,2,3-Triazole-containing uracil derivatives with excellent pharmacokinetics as a novel class of potent human deoxyuridine triphosphatase inhibitors.EBI
Taiho Pharmaceutical
20
Discovery of highly potent human deoxyuridine triphosphatase inhibitors based on the conformation restriction strategy.EBI
Taiho Pharmaceutical
19
Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.EBI
Taiho Pharmaceutical
44
Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors.EBI
Taiho Pharmaceutical
48
Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target.EBI
Cardiff University
19
β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.EBI
University of Dundee
14
Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase.EBI
University of Wales Cardiff
2
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.EBI
University of Cambridge
3
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.EBI
Johann Wolfgang Goethe University
40
Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.EBI
Cardiff University
47
N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonistsBDB
Ogeda
4
Competition of leukotrienes and ICI-198,615 for [3H]LTD4 binding sites in guinea pig lung membranes suggests the involvement of two LTD4 receptor subtypes.BDB
Pfizer
42
NITROGEN-CONTAINING COMPOUND AND USE THEREOFBDB
Suzhou Genhouse Bio Co.