17 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
49
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEd prenyl binding site.
Max Planck Institute of Molecular Physiology
20
Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells.
Shanghai University
20
Non-kinase off-target inhibitory activities of clinically-relevant kinase inhibitors.
Purdue University
22
An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth.
University of Luxembourg
4
Hydrophobic tag-based protein degradation: Development, opportunity and challenge.
China Pharmaceutical University
14
Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC).
East China University of Science and Technology
33
"Hit" to lead optimization and chemoinformatic studies for a new series of Autotaxin inhibitors.
Bioinnovation Institute
147
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Central South University
14
Hydrophobic Tagging-Induced Degradation of PDEδ in Colon Cancer Cells.
Second Military Medical University
13
Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer.
Second Military Medical University
17
Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors.
Janssen Research & Development
25
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction.
Chinese Academy of Sciences
30
Discovery of Novel KRAS-PDEδ Inhibitors by Fragment-Based Drug Design.
Second Military Medical University
17
Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors.
Second Military Medical University
