BDBM50222771 3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide::CHEMBL399318::Chlorantraniliprole

SMILES CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

InChI Key InChIKey=PSOVNZZNOMJUBI-UHFFFAOYSA-N

Data  3 IC50  4 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50222771   

TargetRyanodine receptor(Drosophila melanogaster)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  40nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor in Sf9 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 1(Mus musculus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  1.40E+4nMAssay Description:Activation of ryanodine receptor 1 in mouse C2C12 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
TargetRyanodine receptor(Drosophila melanogaster)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  0.0500nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor(Bemisia tabaci)
Syngenta Crop Protection M£Nchwilen

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to Myzus persicae (green peach aphid) ryanodine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor(Bemisia tabaci)
Syngenta Crop Protection M£Nchwilen

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataIC50:  4.13E+3nMAssay Description:Displacement of [3H]-Tritium-N-(4-chloro-2-methyl-6-(methylcarbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodien receptor(Spodoptera exigua)
Syngenta Crop Protection Muenchwilen

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataIC50:  6.20E+3nMAssay Description:Displacement of [3H]-Tritium-N-(4-chloro-2-methyl-6-(methylcarbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor 2(Rattus norvegicus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of ryanodine receptor 2 in rat PC12 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed