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Found 4 Enz. Inhib. hit(s) with Target = 'Ryanodine receptor' and Ligand = 'BDBM50222771'
TargetRyanodine receptor(Bemisia tabaci)
Syngenta Crop Protection M£Nchwilen

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to Myzus persicae (green peach aphid) ryanodine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor(Bemisia tabaci)
Syngenta Crop Protection M£Nchwilen

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataIC50:  4.13E+3nMAssay Description:Displacement of [3H]-Tritium-N-(4-chloro-2-methyl-6-(methylcarbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor(Drosophila melanogaster)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  40nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor in Sf9 cells assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRyanodine receptor(Drosophila melanogaster)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50222771(3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)ph...)
Affinity DataEC50:  0.0500nMAssay Description:Activation of Drosophila melanogaster ryanodine receptor assessed as induction of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed