BDBM621739 BDBM621797::US11802122, Example 3A::US20230312522, Compound 3::US20230312522, Compound 5
SMILES FC(F)c1nc(ccc1Cl)C(NC(=O)[C@@H]1CNC(=O)N1)c1cnc(c(Cl)c1)C(F)(F)F
InChI Key InChIKey=HTNVQQVGOLYPHY-VUWPPUDQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 621739
Affinity DataIC50: 9.70nMAssay Description:The following buffers were used for the QubeŽ recordings: External buffer for NaV1.8 QubeŽ recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 1...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Compounds were tested on human NaV1.8 and NaV1.5 channels stably expressed in human embryo kidney (HEK) 293 cells. Sodium current measurements on Qub...More data for this Ligand-Target Pair