BDBM143758 US10183953, Example 19::US8969352, 19::US9611277, Example 19::US9845333, 19

SMILES Fc1ccc(-c2ncccn2)c(c1)C(=O)N1CC2CC(Oc3ccc(cn3)C(F)(F)F)C1C2

InChI Key InChIKey=MSBDPMYPBOZFHI-UHFFFAOYSA-N

Data  21 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 143758   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143758(US10183953, Example 19 | US8969352, 19 | US9611277...)
Affinity DataKi:  9nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
TBA

US Patent
LigandPNGBDBM143758(US10183953, Example 19 | US8969352, 19 | US9611277...)
Affinity DataKi:  18nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Rattus norvegicus (Rat))
TBA

US Patent
LigandPNGBDBM143758(US10183953, Example 19 | US8969352, 19 | US9611277...)
Affinity DataKi:  945nMAssay Description:Human Orexin 2 Receptor:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hycl...More data for this Ligand-Target Pair
In DepthDetails US Patent