BDBM143758 US10183953, Example 19::US8969352, 19::US9611277, Example 19::US9845333, 19
SMILES Fc1ccc(-c2ncccn2)c(c1)C(=O)N1CC2CC(Oc3ccc(cn3)C(F)(F)F)C1C2
InChI Key InChIKey=MSBDPMYPBOZFHI-UHFFFAOYSA-N
Data 21 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 143758
Affinity DataKi: 9nM ΔG°: -10.2kcal/moleT: 2°CAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM 001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -9.81kcal/moleT: 2°CAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM 001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
Affinity DataKi: 945nMAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...More data for this Ligand-Target Pair