BDBM50369345 CHEMBL4165724::US11207431, Example 1::US11890356, Example 1

SMILES CN(Cc1ccc(cc1F)C(=O)NO)CC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=IGZQZELTOHAHNW-UHFFFAOYSA-N

Data  49 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50369345   

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 90 mins using fluorogenic substrate ZMAL (Z-Lys(Ac)-AMC) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 90 mins using fluorogenic substrate ZMAL (Z-Lys(Ac)-AMC) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed