BDBM50369345 CHEMBL4165724::US11207431, Example 1::US11890356, Example 1

SMILES CN(Cc1ccc(cc1F)C(=O)NO)CC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=IGZQZELTOHAHNW-UHFFFAOYSA-N

Data  49 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50369345   

TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  16nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  7.10nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.00E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  8.50E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.13E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.13E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  1.90E+4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  4.70E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  5.20E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50:  60nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent