BDBM21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1

SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1

InChI Key InChIKey=LNEPOXFFQSENCJ-UHFFFAOYSA-N

Data  998 KI  170 IC50  4 Kd  4 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 21398   

LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity against serotonin-1 receptor in rat brain using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  33nMAssay Description:Binding affinity against serotonin-2 receptor in rat brain using [3H]spiroperidolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  54nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in rat brain using [3H]- WB-4101More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  6.00E+3nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in rat brain using [3H]- clonidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity against dopamine receptor in rat striatal membrane using [3H]haloperidolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  6.60E+3nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor in rat brain using [3H]- QNBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against beta-2 adrenergic receptor in rat brain using [3H]-DHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against beta-1 adrenergic receptor in rat brain using [3H]-DHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed