BDBM50062915 CHEMBL827::METHYLPHENIDATE::methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate::methyl (R)-phenyl[(R)-piperidin-2-yl]acetate

SMILES COC(=O)[C@@H]([C@H]1CCCCN1)c1ccccc1

InChI Key InChIKey=DUGOZIWVEXMGBE-CHWSQXEVSA-N

Data  5 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062915   

TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataIC50:  156nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank