BDBM86633 JNK-IN-8

SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)c(C)c1

InChI Key InChIKey=GJFCSAPFHAXMSF-UXBLZVDNSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 86633   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK3 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  486nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in human HeLa cells after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  338nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in human A375 cells after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50:  1nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed