BDBM5544 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide::6-Cyclohexylmethoxy-2-(4 -sulfamoylanilino)purine::NU6102

SMILES NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1

InChI Key InChIKey=OWXORKPNCHJYOF-UHFFFAOYSA-N

Data  2 KI  14 IC50

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5544   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of Oxford

LigandBDBM5544(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...)Copy SMILESCopy InChI

Affinity DataIC50:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchaseMMDBPC cidPC sidPDBPatentsSimilars

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