BDBM5544 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide::6-Cyclohexylmethoxy-2-(4 -sulfamoylanilino)purine::NU6102
SMILES NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1
InChI Key InChIKey=OWXORKPNCHJYOF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 5544
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant ZAP70 using EEEEYEEEE as substrate by ESI-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant PYK2 by ESI-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMpH: 7.5 T: 30°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 103nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D,K98T](Human)
University of Oxford
University of Oxford
Affinity DataIC50: 120nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 30°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of ROCK2Checked by AuthorMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of PDK1Checked by AuthorMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of DYRK1aChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMpH: 7.5 T: 30°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair