BDBM50330290 CHEMBL1272326::Cyclohexyl-[4-(3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-amine

SMILES CC(C)c1[nH]ncc1-c1ccnc(NC2CCCCC2)n1

InChI Key InChIKey=LOYSCNBYDPTSAA-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330290   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50330290(CHEMBL1272326 | Cyclohexyl-[4-(3-isopropyl-1H-pyra...)
Affinity DataKi:  18nMAssay Description:Inhibition of human full length GST-tagged CDK4 (1 to 303(end) amino acids)/Cyclin D3 (1 to 292(end) amino acids) expressed in baculovirus expression...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed