BDBM50581355 CHEMBL5070835
SMILES Fc1cnc2OCC3(CC3)NC(=O)c3cnn4ccc(nc34)N3CCNC[C@@H]3c2c1
InChI Key InChIKey=SHRNMJSKKQHLKT-OAHLLOKOSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50581355
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TrKA (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of TrKA G595R mutant (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TrKA G667C mutant (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair