BDBM435721 US10570155, Compound 25III::US11332479, Compound 25III
SMILES Oc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCNS(=O)(=O)c2ccc(F)cc2)n1
InChI Key InChIKey=YDYJBUHNTGURQT-UHFFFAOYSA-N
Data 17 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 435721
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre (Nrc)
Curated by ChEMBL
National Research Centre (Nrc)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human wild type CRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair