BDBM191640 US9186318, 9
SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCC(=O)NO
InChI Key InChIKey=LYXOBSREVZDKST-UHFFFAOYSA-N
Data 20 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 191640
Affinity DataIC50: >630nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 31nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 12nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 115nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 119nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 172nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 154nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: >630nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: 431nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: 8.94E+3nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibitions of activities of HDAC enzymes by the compounds N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-N1...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Beijing Konruns Pharmaceutical
US Patent
Beijing Konruns Pharmaceutical
US Patent
Affinity DataIC50: 19nMAssay Description:This example shows that the inhibitory activity of the compound, N1'-[3-fluoro-4-[[7-[4-(hydroxyamino)-4-oxobutoxy]-6-methoxy-4-quinolyl]oxy]phenyl]-...More data for this Ligand-Target Pair