BDBM50560790 CHEMBL4741283
SMILES Nc1nccc(COc2ccc3nc(N[C@H]4CCCC[C@@H]4O)sc3c2)c1Cl
InChI Key InChIKey=NGKALCMOLVCFHL-ZFWWWQNUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50560790
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
University Of Texas Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair