BDBM50588796 CHEMBL5197792

SMILES COc1cc2c(Oc3ccc(Nc4nn(C)cc4C(=O)NC4CCCCC4)cc3F)ccnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=QBRQTJMZEYORSP-UHFFFAOYSA-N

Data  5 IC50  17 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50588796   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant AXL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataIC50:  27nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataIC50:  156nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataIC50:  151nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed