BDBM510923 1-methyl-6-{[(aR)-6-(3- cyanobenzamido) spiro[3.3]heptan-2- yl]oxy}-1H- pyrazolo[3,4- b]pyridine-5- carboxamide::US11078197, Example 102::US11673886, Example 102
SMILES Cn1ncc2cc(C(N)=O)c(O[C@H]3C[C@@]4(C[C@@H](C4)NC(=O)c4cccc(c4)C#N)C3)nc12
InChI Key InChIKey=HNNUVEBZNMIFHK-QQMNAOGKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510923
Affinity DataIC50: 8nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair