BDBM595498 US11591319, ID lqr-8-185
SMILES COc1ccc(cc1)C(=O)N1N=C(CC1c1ccco1)c1ccc(NS(C)(=O)=O)cc1
InChI Key InChIKey=MJFLPRMTGXUIEP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 595498
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+3nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair