BDBM595498 US11591319, ID lqr-8-185

SMILES COc1ccc(cc1)C(=O)N1N=C(CC1c1ccco1)c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=MJFLPRMTGXUIEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595498   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM595498(US11591319, ID lqr-8-185)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeclin 1/Bcl-2(Homo sapiens)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM595498(US11591319, ID lqr-8-185)
Affinity DataIC50:  9.90E+3nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent