BDBM50311017 CHEMBL1078178::Momelotinib::N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide::US10112907, Example 00019::US10766894, Compound TABLE 1.4::US11203595, TABLE 1.4::US9469613, CYT-0387
SMILES O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
InChI Key InChIKey=ZVHNDZWQTBEVRY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50311017
Affinity DataKd: 3.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
Affinity DataIC50: 405nM Kd: 1.00E+3nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 107nM Kd: 19nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 205nM Kd: 670nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Inhibition of NEK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Inhibition of NEK3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Inhibition of NEK9 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataIC50: 8nM Kd: 25nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair