BDBM50386812 AMITIFADINE HYDROCHLORIDE::DOV 21947::DOV-21947::EB-1010::US9944618, Compound ID No. 179

SMILES Clc1ccc(cc1Cl)[C@@]12C[C@@H]1CNC2

InChI Key InChIKey=BSMNRYCSBFHEMQ-KCJUWKMLSA-N

Data  3 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50386812   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataKi:  38.6nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataKi:  42.3nMAssay Description:DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataKi:  59nMAssay Description:SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...More data for this Ligand-Target Pair
In DepthDetails US Patent