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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50386812'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataKi:  42.3nMAssay Description:DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataIC50:  159nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM50386812(AMITIFADINE HYDROCHLORIDE | DOV 21947 | DOV-21947 ...)
Affinity DataIC50:  159nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in CHO cells after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed