BDBM4831 1-{2-amino-6-[3,5-bis(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-yl}-3-tert-butylurea::CHEMBL49658::PD089828 analog 12
SMILES CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=YRATUKRSRQKZSM-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 4831
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against platelet-derived growth factor receptorMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of chicken c-Src tyrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Parke-Davis Pharmaceutical Research
Affinity DataIC50: >5.00E+4nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labeled ATP to the poly (E: Y) subs...More data for this Ligand-Target Pair