BDBM50032964 (R)-4-Amino-3-(4-chloro-phenyl)-butyric acid::4-Amino-3-(4-chloro-phenyl)-butyric acid::BACLOFEN::CHEMBL301742
SMILES NC[C@H](CC(O)=O)c1ccc(Cl)cc1
InChI Key InChIKey=KPYSYYIEGFHWSV-QMMMGPOBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50032964
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rat)
The Royal Danish School of Pharmacy
Curated by ChEMBL
The Royal Danish School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair